| SP | Garcia, B.Garcia, Bryan >> | 27 | 2022 | R | 76 | 38 | 37 | 16 | 9 | 2.95 | .293 | 1.21 | 6.9 | 4.0 | 8.1 | 201.1 | 153 | 67 | 66 | 23 | 90 | 180 | 0 | 0 | 0 | 0 | 13 | 7 | 3 | 4.14 |
| SP | Bassitt, C.Bassitt, Chris >> | 33 | 2022 | R | 74 | 33 | 32 | 9 | 15 | 4.35 | .333 | 1.44 | 10.1 | 2.9 | 8.0 | 198.2 | 223 | 103 | 96 | 15 | 63 | 176 | 1 | 0 | 0 | 0 | 20 | 12 | 6 | 3.34 |
| SP | Skubal, T.Skubal, Tarik # >> | 25 | 2022 | L | 73 | 25 | 24 | 8 | 7 | 4.84 | .314 | 1.36 | 8.9 | 3.5 | 10.8 | 135.2 | 133 | 74 | 73 | 16 | 52 | 162 | 1 | 1 | 0 | 1 | 9 | 1 | 2 | 3.32 |
| CL | Schreiber, J.Schreiber, John >> | 28 | 2022 | R | 93 | 75 | 0 | 2 | 8 | 2.82 | .265 | 1.05 | 7.1 | 2.5 | 9.7 | 79.2 | 62 | 25 | 25 | 6 | 22 | 85 | 0 | 46 | 6 | 0 | 0 | 2 | 1 | 2.75 |
| SU | Tinoco, J.Tinoco, Jesus >> | 27 | 2022 | R | 84 | 87 | 0 | 5 | 3 | 2.48 | .300 | 1.25 | 7.1 | 4.2 | 7.3 | 94.1 | 74 | 27 | 26 | 2 | 44 | 76 | 0 | 3 | 6 | 0 | 0 | 3 | 0 | 3.16 |
| RP | Jimenez, J.Jimenez, Joe >> | 27 | 2022 | R | 73 | 94 | 0 | 8 | 5 | 2.12 | .255 | 1.00 | 7.3 | 1.7 | 13.4 | 102.0 | 83 | 29 | 24 | 11 | 19 | 152 | 0 | 1 | 6 | 0 | 0 | 3 | 0 | 2.07 |
| RP | Alexander, T.Alexander, Tyler >> | 27 | 2022 | L | 24 | 102 | 0 | 7 | 2 | 2.37 | .273 | 1.09 | 7.9 | 2.0 | 7.8 | 110.1 | 96 | 29 | 29 | 6 | 24 | 95 | 0 | 2 | 5 | 0 | 0 | 4 | 0 | 2.75 |
| RP | Englert, M.Englert, Mason >> | 23 | 2023 | R | 10 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Manning, M.Manning, Matt >> | 24 | 2022 | R | 67 | 42 | 0 | 8 | 5 | 3.67 | .316 | 1.34 | 8.6 | 3.5 | 6.4 | 115.1 | 110 | 48 | 47 | 15 | 45 | 82 | 0 | 2 | 1 | 0 | 0 | 5 | 3 | 4.57 |
| SP | Turnbull, S.Turnbull, Spencer >> | 30 | 2023 | R | 6 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Holton, T.Holton, Tyler >> | 27 | 2023 | L | 93 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | White, B.White, Brendan >> | 24 | 2023 | R | 29 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Gipson-Long, S.Gipson-Long, Sawyer >> | 25 | 2023 | R | 91 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |