| SP | Skubal, T.Skubal, Tarik # $$ >> | 28 | 2025 | L | 100 | 32 | 32 | 10 | 8 | 3.86 | .282 | 1.14 | 8.5 | 1.8 | 9.8 | 175.0 | 165 | 75 | 75 | 17 | 35 | 190 | 0 | 0 | 0 | 0 | 13 | 6 | 1 | 2.79 |
| SP | Rasmussen, D.Rasmussen, Drew >> | 29 | 2025 | R | 85 | 30 | 30 | 7 | 14 | 5.67 | .364 | 1.69 | 11.5 | 3.7 | 8.4 | 125.1 | 160 | 81 | 79 | 18 | 52 | 117 | 0 | 0 | 0 | 0 | 2 | 3 | 2 | 4.32 |
| RP | Pagan, E.Pagan, Emilio # >> | 34 | 2025 | R | 95 | 91 | 0 | 4 | 3 | 4.21 | .306 | 1.26 | 7.9 | 3.5 | 11.5 | 113.1 | 99 | 53 | 53 | 15 | 44 | 144 | 0 | 1 | 6 | 0 | 0 | 7 | 0 | 3.53 |
| SU | Santana, D.Santana, Dennis >> | 29 | 2025 | R | 92 | 93 | 0 | 5 | 4 | 3.08 | .302 | 1.28 | 7.8 | 3.8 | 8.0 | 105.1 | 91 | 43 | 36 | 15 | 44 | 93 | 0 | 2 | 4 | 0 | 0 | 2 | 0 | 4.40 |
| RP | Keller, B.Keller, Brad >> | 29 | 2025 | R | 88 | 90 | 0 | 8 | 1 | 3.40 | .267 | 1.05 | 6.6 | 2.8 | 11.7 | 95.1 | 70 | 36 | 36 | 9 | 30 | 124 | 0 | 0 | 5 | 0 | 0 | 4 | 0 | 2.69 |
| RP | Sousa, B.Sousa, Bennett >> | 30 | 2025 | L | 80 | 102 | 0 | 4 | 4 | 4.68 | .327 | 1.44 | 8.9 | 4.0 | 10.6 | 98.0 | 97 | 51 | 51 | 16 | 44 | 115 | 0 | 0 | 1 | 0 | 0 | 2 | 4 | 4.18 |
| CL | Abreu, B.Abreu, Bryan † # >> | 28 | 2025 | R | 73 | 81 | 0 | 1 | 6 | 4.61 | .306 | 1.26 | 7.0 | 4.4 | 10.9 | 80.0 | 62 | 41 | 41 | 11 | 39 | 97 | 0 | 38 | 8 | 0 | 0 | 5 | 4 | 4.01 |
| RP | Coulombe, D.Coulombe, Daniel $$ >> | 35 | 2025 | L | 62 | 88 | 0 | 5 | 4 | 5.34 | .338 | 1.52 | 9.4 | 4.3 | 9.9 | 87.2 | 91 | 53 | 52 | 23 | 42 | 96 | 0 | 3 | 1 | 0 | 0 | 1 | 4 | 5.71 |