| SP | Maddux, G.Maddux, Greg $$ >> | 29 | 1995 | R | 89 | 35 | 35 | 13 | 14 | 4.96 | .310 | 1.32 | 9.8 | 2.1 | 6.4 | 230.1 | 251 | 136 | 127 | 37 | 53 | 163 | 4 | 0 | 0 | 0 | 15 | 7 | 8 | 4.46 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 34 | 34 | 10 | 16 | 4.38 | .307 | 1.30 | 9.8 | 1.9 | 4.9 | 226.0 | 246 | 116 | 110 | 24 | 48 | 122 | 3 | 0 | 0 | 0 | 16 | 6 | 2 | 4.02 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 29 | 29 | 10 | 11 | 4.69 | .308 | 1.30 | 8.3 | 3.4 | 5.9 | 186.0 | 171 | 98 | 97 | 26 | 71 | 122 | 1 | 0 | 0 | 1 | 13 | 6 | 7 | 4.75 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 85 | 0 | 8 | 3 | 4.38 | .307 | 1.32 | 9.6 | 2.3 | 8.5 | 100.2 | 107 | 50 | 49 | 11 | 26 | 94 | 0 | 2 | 3 | 0 | 0 | 1 | 4 | 3.36 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 60 | 0 | 8 | 2 | 4.07 | .308 | 1.34 | 7.5 | 4.6 | 10.8 | 55.1 | 46 | 26 | 25 | 7 | 28 | 66 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 3.78 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 25 | 0 | 0 | 2 | 2.49 | .255 | 1.03 | 6.8 | 2.5 | 3.6 | 25.1 | 19 | 7 | 7 | 2 | 7 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.08 |
| CL | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 98 | 74 | 0 | 7 | 7 | 3.77 | .303 | 1.29 | 7.1 | 4.5 | 9.4 | 86.0 | 68 | 36 | 36 | 11 | 43 | 90 | 0 | 43 | 4 | 0 | 0 | 1 | 0 | 4.10 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 21 | 3 | 5 | 2 | 4.43 | .310 | 1.33 | 8.9 | 3.1 | 5.3 | 101.2 | 100 | 50 | 50 | 10 | 35 | 60 | 0 | 0 | 0 | 0 | 2 | 2 | 2 | 4.20 |