| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 28 | 28 | 11 | 11 | 4.65 | .295 | 1.24 | 8.2 | 2.9 | 7.6 | 186.0 | 170 | 97 | 96 | 24 | 60 | 158 | 7 | 0 | 0 | 1 | 11 | 3 | 7 | 3.99 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 27 | 27 | 12 | 10 | 4.22 | .316 | 1.37 | 8.9 | 3.5 | 5.2 | 185.2 | 182 | 91 | 87 | 22 | 72 | 106 | 5 | 0 | 0 | 1 | 15 | 3 | 1 | 4.62 |
| SP | Snell, B.Snell, Blake † >> | 25 | 2018 | L | 81 | 27 | 27 | 15 | 5 | 3.35 | .274 | 1.12 | 6.2 | 3.8 | 6.6 | 164.0 | 113 | 63 | 61 | 14 | 70 | 121 | 0 | 0 | 0 | 0 | 20 | 3 | 0 | 3.97 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 29 | 27 | 7 | 13 | 5.29 | .317 | 1.37 | 9.1 | 3.2 | 5.5 | 153.0 | 155 | 92 | 90 | 26 | 54 | 94 | 3 | 1 | 0 | 0 | 12 | 4 | 1 | 5.12 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 84 | 0 | 4 | 2 | 3.33 | .303 | 1.29 | 6.5 | 5.1 | 8.8 | 51.1 | 37 | 21 | 19 | 5 | 29 | 50 | 0 | 4 | 2 | 0 | 0 | 1 | 2 | 4.08 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 76 | 0 | 3 | 0 | 2.57 | .292 | 1.21 | 7.7 | 3.1 | 7.6 | 63.0 | 54 | 21 | 18 | 5 | 22 | 53 | 0 | 3 | 3 | 0 | 0 | 2 | 0 | 3.49 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 64 | 0 | 1 | 1 | 4.85 | .308 | 1.33 | 7.4 | 4.6 | 10.2 | 39.0 | 32 | 21 | 21 | 3 | 20 | 44 | 0 | 7 | 2 | 0 | 0 | 0 | 1 | 3.28 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 74 | 51 | 0 | 4 | 2 | 3.86 | .312 | 1.34 | 8.8 | 3.5 | 9.5 | 39.2 | 38 | 17 | 17 | 4 | 15 | 41 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 3.46 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 32 | 0 | 4 | 3 | 2.70 | .294 | 1.25 | 7.4 | 3.8 | 5.0 | 40.0 | 33 | 19 | 12 | 2 | 17 | 22 | 0 | 4 | 2 | 0 | 0 | 0 | 5 | 3.83 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 56 | 0 | 3 | 0 | 2.23 | .281 | 1.15 | 8.0 | 2.5 | 6.3 | 44.1 | 39 | 12 | 11 | 3 | 12 | 31 | 0 | 5 | 0 | 0 | 0 | 1 | 4 | 3.36 |