| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 29 | 29 | 6 | 15 | 4.97 | .330 | 1.45 | 9.3 | 3.7 | 5.9 | 163.0 | 169 | 111 | 90 | 20 | 67 | 107 | 0 | 0 | 0 | 0 | 14 | 5 | 4 | 4.61 |
| SP | Weaver, J.Weaver, Jered >> | 24 | 2006 | R | 83 | 28 | 28 | 12 | 12 | 5.55 | .326 | 1.43 | 9.6 | 3.4 | 8.1 | 160.2 | 170 | 113 | 99 | 27 | 60 | 144 | 0 | 0 | 0 | 0 | 12 | 3 | 3 | 4.58 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 60 | 28 | 28 | 5 | 18 | 6.75 | .375 | 1.77 | 12.7 | 3.2 | 7.1 | 160.0 | 226 | 163 | 120 | 36 | 57 | 126 | 2 | 0 | 0 | 0 | 8 | 5 | 3 | 5.51 |
| SP | Colon, B.Colon, Bartolo >> | 32 | 2005 | R | 22 | 27 | 26 | 2 | 14 | 8.44 | .387 | 1.87 | 13.6 | 3.2 | 6.6 | 133.1 | 201 | 146 | 125 | 33 | 48 | 97 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 5.92 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 88 | 93 | 0 | 6 | 5 | 3.83 | .322 | 1.40 | 8.4 | 4.2 | 7.8 | 115.0 | 107 | 58 | 49 | 9 | 54 | 100 | 0 | 2 | 9 | 0 | 0 | 3 | 2 | 3.77 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 70 | 0 | 2 | 8 | 4.00 | .320 | 1.40 | 9.1 | 3.5 | 10.9 | 74.1 | 75 | 40 | 33 | 10 | 29 | 90 | 0 | 9 | 3 | 0 | 0 | 1 | 5 | 3.54 |
| RP | Sasaki, K.Sasaki, Kazuhiro >> | 33 | 2001 | R | 64 | 68 | 0 | 3 | 0 | 3.04 | .292 | 1.23 | 7.1 | 3.9 | 7.1 | 71.0 | 56 | 30 | 24 | 9 | 31 | 56 | 0 | 6 | 0 | 0 | 0 | 1 | 2 | 4.42 |