| SP | Clemens, R.Clemens, Roger # >> | 43 | 2005 | R | 94 | 34 | 34 | 12 | 12 | 4.48 | .313 | 1.32 | 8.3 | 3.5 | 7.1 | 199.0 | 184 | 101 | 99 | 20 | 78 | 158 | 1 | 0 | 0 | 0 | 16 | 10 | 2 | 4.05 |
| SP | Weaver, J.Weaver, Jered # >> | 24 | 2006 | R | 83 | 33 | 33 | 8 | 15 | 6.43 | .344 | 1.54 | 10.4 | 3.6 | 6.4 | 159.2 | 183 | 114 | 114 | 35 | 63 | 113 | 0 | 0 | 0 | 0 | 14 | 5 | 4 | 5.72 |
| SP | Hamels, C.Hamels, Cole # >> | 25 | 2008 | L | 72 | 32 | 32 | 9 | 11 | 6.26 | .331 | 1.45 | 10.1 | 3.1 | 6.1 | 162.1 | 181 | 115 | 113 | 37 | 55 | 110 | 1 | 0 | 0 | 0 | 9 | 5 | 0 | 5.72 |
| SP | Kazmir, S.Kazmir, Scott # >> | 24 | 2008 | L | 39 | 16 | 16 | 3 | 6 | 6.18 | .372 | 1.78 | 11.5 | 4.6 | 10.6 | 71.1 | 91 | 57 | 49 | 14 | 36 | 84 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 4.72 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 94 | 0 | 6 | 2 | 3.79 | .308 | 1.29 | 9.0 | 2.7 | 9.0 | 137.2 | 137 | 60 | 58 | 17 | 41 | 137 | 0 | 3 | 5 | 0 | 0 | 6 | 0 | 3.64 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 87 | 90 | 0 | 5 | 4 | 2.74 | .296 | 1.22 | 7.8 | 3.2 | 7.0 | 128.1 | 111 | 43 | 39 | 7 | 46 | 100 | 0 | 7 | 2 | 0 | 0 | 5 | 3 | 3.34 |
| RP | Betancourt, R.Betancourt, Rafael # >> | 32 | 2007 | R | 86 | 81 | 0 | 7 | 10 | 4.71 | .286 | 1.18 | 8.8 | 1.8 | 9.3 | 109.0 | 107 | 57 | 57 | 18 | 22 | 113 | 0 | 6 | 7 | 0 | 0 | 2 | 0 | 3.73 |
| RP | Percival, T.Percival, Troy >> | 38 | 2007 | R | 84 | 76 | 0 | 4 | 3 | 3.74 | .301 | 1.26 | 6.1 | 5.3 | 6.7 | 89.0 | 60 | 38 | 37 | 5 | 52 | 66 | 0 | 4 | 3 | 0 | 0 | 3 | 3 | 4.10 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 73 | 52 | 0 | 3 | 1 | 6.05 | .351 | 1.60 | 11.8 | 2.6 | 9.8 | 58.0 | 76 | 39 | 39 | 15 | 17 | 63 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 5.12 |
| SP | Maddux, G.Maddux, Greg # >> | 34 | 2000 | R | 57 | 29 | 15 | 3 | 7 | 7.15 | .357 | 1.63 | 11.7 | 3.1 | 6.5 | 90.2 | 117 | 72 | 72 | 24 | 31 | 65 | 2 | 1 | 0 | 0 | 4 | 3 | 1 | 6.16 |