| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 31 | 31 | 10 | 13 | 4.57 | .317 | 1.37 | 9.3 | 3.1 | 10.6 | 200.2 | 206 | 106 | 102 | 26 | 69 | 236 | 2 | 0 | 0 | 1 | 18 | 5 | 2 | 3.44 |
| SP | Darvish, Y.Darvish, Yu # >> | 26 | 2013 | R | 79 | 30 | 30 | 11 | 10 | 3.53 | .312 | 1.33 | 8.6 | 3.4 | 10.2 | 201.1 | 192 | 90 | 79 | 19 | 75 | 227 | 1 | 0 | 0 | 0 | 21 | 7 | 4 | 3.19 |
| SP | Keuchel, D.Keuchel, Dallas # >> | 27 | 2015 | L | 69 | 29 | 29 | 10 | 12 | 5.56 | .339 | 1.49 | 10.5 | 2.9 | 7.8 | 183.0 | 213 | 117 | 113 | 37 | 59 | 158 | 4 | 0 | 0 | 2 | 10 | 9 | 4 | 5.02 |
| SP | Gonzalez, G.Gonzalez, Gio >> | 27 | 2012 | L | 46 | 28 | 28 | 10 | 12 | 5.99 | .362 | 1.68 | 9.2 | 5.9 | 8.9 | 147.1 | 150 | 103 | 98 | 22 | 97 | 145 | 0 | 0 | 0 | 0 | 10 | 4 | 8 | 5.03 |
| RP | Kuo, H.Kuo, Hong-Chih † >> | 29 | 2010 | L | 93 | 80 | 0 | 6 | 3 | 1.71 | .261 | 1.04 | 6.1 | 3.4 | 10.7 | 110.1 | 74 | 21 | 21 | 4 | 41 | 131 | 0 | 5 | 2 | 0 | 0 | 2 | 1 | 2.26 |
| RP | Petit, Y.Petit, Yusmeiro >> | 35 | 2019 | R | 71 | 72 | 0 | 4 | 7 | 2.83 | .285 | 1.18 | 8.7 | 1.9 | 6.9 | 98.2 | 95 | 31 | 31 | 9 | 21 | 75 | 0 | 9 | 2 | 0 | 0 | 2 | 2 | 3.37 |
| RP | Rivero, F.Rivero, Felipe >> | 27 | 2019 | L | 47 | 56 | 0 | 4 | 2 | 3.63 | .285 | 1.18 | 7.7 | 3.0 | 11.0 | 67.0 | 57 | 27 | 27 | 8 | 22 | 82 | 0 | 7 | 0 | 0 | 0 | 1 | 1 | 3.13 |
| RP | Neris, H.Neris, Hector >> | 30 | 2019 | R | 37 | 51 | 0 | 6 | 4 | 3.77 | .317 | 1.38 | 9.5 | 3.0 | 9.9 | 57.1 | 60 | 25 | 24 | 8 | 19 | 63 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 3.67 |
| RP | Barraclough, K.Barraclough, Kyle >> | 26 | 2016 | R | 28 | 40 | 0 | 2 | 1 | 4.72 | .322 | 1.43 | 5.7 | 7.3 | 10.1 | 47.2 | 30 | 26 | 25 | 3 | 38 | 53 | 0 | 2 | 0 | 0 | 0 | 0 | 7 | 4.00 |
| SP | Paxton, J.Paxton, James >> | 29 | 2018 | L | 45 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Romero, R.Romero, Ricky >> | 26 | 2011 | L | 35 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |