| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 98 | 31 | 31 | 16 | 7 | 4.23 | .304 | 1.28 | 8.5 | 3.1 | 10.0 | 206.1 | 194 | 102 | 97 | 25 | 71 | 230 | 1 | 0 | 0 | 0 | 18 | 5 | 1 | 3.45 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 81 | 30 | 30 | 11 | 12 | 5.47 | .343 | 1.53 | 9.8 | 4.0 | 6.4 | 172.2 | 188 | 110 | 105 | 29 | 77 | 122 | 0 | 0 | 0 | 0 | 13 | 6 | 6 | 5.22 |
| SP | Giolito, L.Giolito, Lucas # >> | 24 | 2019 | R | 72 | 30 | 30 | 8 | 8 | 6.71 | .345 | 1.54 | 9.9 | 4.0 | 10.1 | 158.1 | 174 | 121 | 118 | 44 | 70 | 178 | 0 | 0 | 0 | 0 | 7 | 6 | 4 | 5.81 |
| SP | Bauer, T.Bauer, Trevor >> | 27 | 2018 | R | 59 | 30 | 30 | 9 | 9 | 5.26 | .334 | 1.48 | 9.7 | 3.7 | 10.4 | 172.2 | 185 | 109 | 101 | 21 | 71 | 198 | 1 | 0 | 0 | 1 | 11 | 4 | 7 | 3.59 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 59 | 0 | 4 | 3 | 5.05 | .321 | 1.42 | 9.3 | 3.5 | 9.3 | 57.0 | 59 | 35 | 32 | 13 | 22 | 59 | 0 | 31 | 11 | 0 | 0 | 0 | 3 | 5.05 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 81 | 78 | 0 | 9 | 3 | 3.03 | .260 | 1.05 | 6.6 | 2.9 | 9.9 | 115.2 | 84 | 51 | 39 | 10 | 37 | 127 | 0 | 2 | 6 | 0 | 0 | 1 | 3 | 2.91 |
| RP | Soriano, R.Soriano, Rafael >> | 31 | 2010 | R | 79 | 61 | 0 | 6 | 4 | 4.06 | .336 | 1.49 | 9.4 | 4.1 | 8.1 | 71.0 | 74 | 34 | 32 | 12 | 32 | 64 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 4.83 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 75 | 59 | 0 | 0 | 5 | 5.79 | .355 | 1.61 | 9.7 | 4.8 | 10.2 | 65.1 | 70 | 44 | 42 | 13 | 35 | 74 | 0 | 3 | 3 | 0 | 0 | 3 | 2 | 5.08 |
| RP | Thornburg, T.Thornburg, Tyler >> | 27 | 2016 | R | 66 | 45 | 0 | 1 | 4 | 3.76 | .319 | 1.35 | 6.9 | 5.4 | 10.2 | 52.2 | 40 | 22 | 22 | 7 | 31 | 59 | 0 | 2 | 2 | 0 | 0 | 3 | 6 | 4.44 |
| RP | Janssen, C.Janssen, Casey >> | 31 | 2012 | R | 55 | 35 | 0 | 3 | 2 | 4.19 | .314 | 1.32 | 9.7 | 2.4 | 11.8 | 38.2 | 41 | 20 | 18 | 10 | 10 | 50 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.74 |
| SP | Wainwright, A.Wainwright, Adam >> | 29 | 2010 | R | 57 | 18 | 13 | 4 | 8 | 6.42 | .350 | 1.58 | 10.2 | 4.0 | 8.7 | 101.0 | 115 | 76 | 72 | 22 | 45 | 98 | 2 | 0 | 0 | 1 | 5 | 3 | 2 | 5.32 |