| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 98 | 20 | 20 | 9 | 8 | 4.74 | .314 | 1.34 | 8.7 | 3.3 | 8.7 | 129.0 | 125 | 69 | 68 | 24 | 48 | 125 | 0 | 0 | 0 | 0 | 9 | 4 | 2 | 4.69 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 89 | 19 | 19 | 9 | 7 | 3.66 | .301 | 1.26 | 8.2 | 3.2 | 6.5 | 140.0 | 127 | 64 | 57 | 18 | 50 | 101 | 4 | 0 | 0 | 0 | 13 | 4 | 2 | 4.39 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 77 | 19 | 19 | 8 | 7 | 5.18 | .330 | 1.45 | 9.7 | 3.3 | 7.8 | 113.0 | 122 | 66 | 65 | 24 | 42 | 98 | 0 | 0 | 0 | 0 | 9 | 3 | 5 | 5.22 |
| SP | Hamels, C.Hamels, Cole # >> | 28 | 2011 | L | 79 | 19 | 19 | 8 | 6 | 5.32 | .342 | 1.52 | 10.3 | 3.4 | 7.3 | 113.1 | 129 | 69 | 67 | 14 | 43 | 92 | 1 | 0 | 0 | 0 | 9 | 5 | 2 | 4.26 |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 71 | 18 | 18 | 7 | 6 | 4.80 | .326 | 1.42 | 10.3 | 2.6 | 6.5 | 125.2 | 143 | 69 | 67 | 13 | 36 | 90 | 1 | 0 | 0 | 0 | 8 | 3 | 1 | 3.85 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 50 | 0 | 2 | 1 | 3.21 | .277 | 1.14 | 6.2 | 4.1 | 10.8 | 61.2 | 42 | 22 | 22 | 8 | 28 | 73 | 0 | 8 | 1 | 0 | 0 | 1 | 1 | 3.74 |
| RP | Petit, Y.Petit, Yusmeiro >> | 35 | 2019 | R | 71 | 16 | 0 | 1 | 1 | 7.80 | .384 | 1.67 | 12.0 | 3.0 | 3.0 | 15.0 | 20 | 13 | 13 | 3 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 6.53 |
| RP | O'Day, D.O'Day, Darren >> | 32 | 2014 | R | 65 | 9 | 0 | 1 | 1 | 4.61 | .255 | 1.02 | 6.9 | 2.8 | 9.7 | 13.2 | 10 | 7 | 7 | 3 | 4 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.77 |
| SP | Romero, R.Romero, Ricky >> | 26 | 2011 | L | 37 | 2 | 0 | 0 | 0 | 2.84 | .367 | 1.74 | 10.5 | 6.0 | 9.0 | 6.1 | 7 | 2 | 2 | 1 | 4 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.17 |