| SP | Schmidt, J.Schmidt, Jason † $ >> | 30 | 2003 | R | 99 | 18 | 18 | 9 | 6 | 3.72 | .308 | 1.30 | 8.4 | 3.3 | 8.0 | 116.0 | 108 | 50 | 48 | 12 | 43 | 103 | 0 | 0 | 0 | 0 | 11 | 4 | 1 | 3.78 |
| SP | Williams, W.Williams, Woody # $$ >> | 36 | 2002 | R | 79 | 17 | 17 | 9 | 7 | 5.11 | .312 | 1.33 | 9.7 | 2.4 | 7.0 | 107.1 | 115 | 61 | 61 | 18 | 28 | 83 | 0 | 0 | 0 | 0 | 8 | 3 | 1 | 4.50 |
| SP | Alvarez, W.Alvarez, Wilson >> | 33 | 2003 | L | 74 | 17 | 17 | 5 | 4 | 5.81 | .367 | 1.69 | 11.1 | 4.3 | 6.9 | 69.2 | 85 | 48 | 45 | 8 | 33 | 53 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 4.54 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 72 | 16 | 16 | 6 | 7 | 5.58 | .330 | 1.44 | 10.3 | 2.8 | 8.0 | 88.2 | 101 | 56 | 55 | 16 | 27 | 78 | 0 | 0 | 0 | 0 | 8 | 3 | 0 | 4.61 |
| CL | Putz, J.Putz, J.J. † $$ >> | 30 | 2007 | R | 99 | 31 | 0 | 3 | 3 | 1.67 | .230 | 0.90 | 6.5 | 1.7 | 9.3 | 32.1 | 23 | 8 | 6 | 3 | 6 | 33 | 0 | 15 | 2 | 0 | 0 | 0 | 2 | 2.72 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 88 | 45 | 0 | 2 | 1 | 2.28 | .257 | 0.97 | 6.3 | 2.5 | 6.7 | 43.1 | 30 | 12 | 11 | 4 | 12 | 32 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 3.77 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 29 | 0 | 1 | 2 | 4.81 | .376 | 1.81 | 7.9 | 8.6 | 10.9 | 24.1 | 21 | 13 | 13 | 4 | 23 | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.63 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 32 | 0 | 1 | 0 | 1.38 | .264 | 1.08 | 7.3 | 2.4 | 8.0 | 26.0 | 21 | 4 | 4 | 2 | 7 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.04 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 73 | 23 | 0 | 0 | 1 | 3.91 | .337 | 1.52 | 9.4 | 4.3 | 6.7 | 23.0 | 24 | 11 | 10 | 3 | 11 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.65 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 70 | 23 | 0 | 1 | 0 | 4.76 | .325 | 1.34 | 8.0 | 4.2 | 10.6 | 28.1 | 25 | 15 | 15 | 1 | 13 | 33 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 2.82 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 67 | 16 | 4 | 2 | 2 | 4.15 | .322 | 1.43 | 9.7 | 3.2 | 5.9 | 73.2 | 79 | 35 | 34 | 13 | 26 | 48 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 5.07 |