| SP | Clemens, R.Clemens, Roger † # >> | 43 | 2005 | R | 94 | 18 | 18 | 6 | 7 | 3.29 | .288 | 1.21 | 7.5 | 3.4 | 7.3 | 126.0 | 105 | 48 | 46 | 14 | 47 | 102 | 4 | 0 | 0 | 2 | 12 | 1 | 3 | 3.97 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 50 | 17 | 17 | 5 | 6 | 3.82 | .321 | 1.41 | 9.1 | 3.7 | 6.7 | 110.2 | 111 | 49 | 47 | 13 | 45 | 82 | 2 | 0 | 0 | 0 | 12 | 1 | 1 | 4.30 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 48 | 17 | 17 | 3 | 7 | 5.95 | .377 | 1.79 | 12.3 | 3.8 | 6.6 | 101.1 | 138 | 68 | 67 | 14 | 43 | 74 | 0 | 0 | 0 | 0 | 6 | 3 | 0 | 4.70 |
| SP | Johnson, J.Johnson, Josh >> | 25 | 2009 | R | 47 | 16 | 16 | 4 | 9 | 6.15 | .369 | 1.73 | 11.1 | 4.6 | 6.6 | 90.2 | 111 | 62 | 62 | 18 | 46 | 66 | 0 | 0 | 0 | 0 | 4 | 2 | 3 | 5.73 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 61 | 42 | 0 | 2 | 4 | 5.92 | .345 | 1.50 | 9.0 | 4.7 | 10.5 | 48.2 | 48 | 34 | 32 | 11 | 25 | 56 | 0 | 3 | 0 | 0 | 0 | 4 | 0 | 5.46 |
| RP | Otsuka, A.Otsuka, Akinori >> | 32 | 2004 | R | 46 | 38 | 0 | 3 | 3 | 5.05 | .317 | 1.37 | 7.0 | 5.3 | 10.1 | 41.0 | 32 | 24 | 23 | 4 | 24 | 46 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.85 |
| RP | Howell, J.Howell, J.P. >> | 25 | 2008 | L | 35 | 35 | 0 | 1 | 0 | 6.91 | .378 | 1.75 | 11.0 | 5.0 | 8.6 | 41.2 | 50 | 33 | 32 | 5 | 23 | 39 | 0 | 3 | 1 | 0 | 0 | 3 | 3 | 4.59 |
| SP | Jimenez, U.Jimenez, Ubaldo | 25 | 2009 | R | 35 | 3 | 0 | 1 | 0 | 0.00 | .143 | 0.50 | 2.3 | 2.3 | 6.8 | 4.0 | 1 | 0 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.25 |
| SP | Person, R.Person, Robert >> | 32 | 2001 | R | 24 | 18 | 0 | 1 | 4 | 6.34 | .359 | 1.62 | 10.1 | 4.8 | 6.8 | 32.2 | 36 | 23 | 23 | 6 | 17 | 24 | 0 | 1 | 1 | 0 | 0 | 2 | 7 | 5.72 |