| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 34 | 34 | 6 | 11 | 4.47 | .319 | 1.38 | 8.8 | 3.6 | 9.1 | 161.0 | 158 | 80 | 80 | 29 | 64 | 163 | 0 | 0 | 0 | 0 | 2 | 4 | 8 | 4.58 |
| SP | Oswalt, R.Oswalt, Roy # >> | 24 | 2001 | R | 71 | 33 | 33 | 9 | 15 | 5.02 | .301 | 1.27 | 9.1 | 2.4 | 8.2 | 177.1 | 179 | 104 | 99 | 34 | 47 | 161 | 0 | 0 | 0 | 0 | 13 | 3 | 0 | 4.53 |
| SP | Beckett, J.Beckett, Josh # >> | 27 | 2007 | R | 48 | 32 | 32 | 15 | 10 | 3.96 | .283 | 1.16 | 8.4 | 2.1 | 7.7 | 223.0 | 207 | 107 | 98 | 42 | 51 | 190 | 4 | 0 | 0 | 1 | 18 | 6 | 3 | 4.51 |
| SP | Johnson, J.Johnson, Josh >> | 25 | 2009 | R | 47 | 31 | 31 | 9 | 15 | 6.16 | .327 | 1.43 | 10.3 | 2.6 | 7.2 | 198.2 | 226 | 141 | 136 | 52 | 58 | 159 | 0 | 0 | 0 | 0 | 10 | 6 | 7 | 5.78 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 87 | 0 | 9 | 5 | 4.28 | .310 | 1.30 | 8.0 | 3.7 | 9.9 | 136.2 | 121 | 65 | 65 | 19 | 56 | 149 | 0 | 11 | 3 | 0 | 0 | 7 | 0 | 4.01 |
| RP | Mantei, M.Mantei, Matt >> | 30 | 2003 | R | 60 | 84 | 0 | 5 | 6 | 4.08 | .341 | 1.50 | 8.1 | 5.4 | 9.7 | 108.0 | 97 | 51 | 49 | 17 | 65 | 116 | 0 | 6 | 4 | 0 | 0 | 6 | 1 | 4.87 |
| RP | Vizcaino, L.Vizcaino, Luis >> | 28 | 2002 | R | 48 | 76 | 0 | 6 | 3 | 3.78 | .275 | 1.14 | 6.4 | 3.9 | 6.9 | 97.2 | 69 | 41 | 41 | 16 | 42 | 74 | 0 | 9 | 2 | 0 | 0 | 0 | 1 | 4.92 |
| RP | Turnbow, D.Turnbow, Derrick >> | 27 | 2005 | R | 39 | 66 | 0 | 7 | 3 | 3.94 | .284 | 1.18 | 6.9 | 3.7 | 6.9 | 82.1 | 63 | 38 | 36 | 9 | 34 | 63 | 0 | 6 | 1 | 0 | 0 | 1 | 6 | 4.17 |
| SP | Verlander, J.Verlander, Justin >> | 26 | 2009 | R | 42 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |