| SP | Skubal, T.Skubal, Tarik $ >> | 28 | 2025 | L | 100 | 26 | 26 | 10 | 10 | 4.54 | .296 | 1.24 | 9.1 | 2.2 | 10.6 | 174.1 | 175 | 89 | 88 | 28 | 42 | 204 | 0 | 0 | 0 | 0 | 14 | 3 | 2 | 3.52 |
| SP | Rodon, C.Rodon, Carlos $ >> | 32 | 2025 | L | 92 | 27 | 27 | 6 | 11 | 4.18 | .308 | 1.32 | 7.8 | 4.1 | 9.7 | 168.0 | 145 | 79 | 78 | 21 | 76 | 181 | 0 | 0 | 0 | 0 | 11 | 3 | 2 | 3.88 |
| SP | Gilbert, L.Gilbert, Logan >> | 28 | 2025 | R | 91 | 26 | 26 | 5 | 9 | 4.07 | .327 | 1.40 | 8.6 | 4.1 | 10.7 | 146.0 | 139 | 66 | 66 | 14 | 66 | 174 | 0 | 0 | 0 | 0 | 7 | 8 | 5 | 3.38 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 82 | 25 | 25 | 3 | 6 | 6.75 | .371 | 1.71 | 11.4 | 4.0 | 7.9 | 112.0 | 142 | 85 | 84 | 25 | 50 | 98 | 0 | 0 | 0 | 0 | 3 | 6 | 2 | 5.65 |
| SP | Abbott, A.Abbott, Andrew >> | 26 | 2025 | L | 71 | 25 | 25 | 8 | 8 | 5.76 | .349 | 1.54 | 10.7 | 3.2 | 8.0 | 140.2 | 167 | 96 | 90 | 26 | 50 | 125 | 0 | 0 | 0 | 0 | 9 | 9 | 2 | 4.89 |
| CL | Svanson, M.Svanson, Matt >> | 26 | 2025 | R | 98 | 58 | 0 | 4 | 8 | 3.10 | .269 | 1.09 | 5.0 | 5.0 | 10.0 | 69.2 | 38 | 24 | 24 | 8 | 38 | 77 | 0 | 29 | 8 | 0 | 0 | 1 | 1 | 3.97 |
| RP | Munoz, A.Munoz, Andres >> | 26 | 2025 | R | 90 | 70 | 0 | 9 | 4 | 3.66 | .334 | 1.46 | 6.6 | 6.5 | 10.1 | 91.0 | 67 | 37 | 37 | 6 | 66 | 102 | 0 | 0 | 3 | 0 | 0 | 4 | 2 | 3.92 |
| RP | Kittredge, A.Kittredge, Andrew >> | 35 | 2025 | R | 83 | 68 | 0 | 7 | 1 | 2.53 | .257 | 1.01 | 7.3 | 1.8 | 11.5 | 92.1 | 75 | 28 | 26 | 7 | 18 | 118 | 0 | 2 | 5 | 0 | 0 | 3 | 1 | 2.11 |
| RP | Megill, T.Megill, Trevor >> | 31 | 2025 | R | 70 | 52 | 0 | 3 | 3 | 4.92 | .315 | 1.29 | 7.4 | 4.3 | 12.2 | 56.2 | 46 | 31 | 31 | 7 | 27 | 76 | 0 | 1 | 2 | 0 | 0 | 5 | 2 | 3.63 |
| RP | Clarke, T.Clarke, Taylor >> | 32 | 2025 | R | 87 | 41 | 0 | 4 | 3 | 2.15 | .250 | 0.98 | 7.4 | 1.4 | 7.6 | 46.0 | 38 | 11 | 11 | 3 | 7 | 39 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 2.67 |