| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 13 | 13 | 6 | 2 | 3.72 | .282 | 1.14 | 7.9 | 2.4 | 9.7 | 94.1 | 83 | 39 | 39 | 11 | 25 | 101 | 0 | 0 | 0 | 0 | 7 | 3 | 0 | 3.27 |
| SP | McKenzie, T.McKenzie, Triston >> | 24 | 2022 | R | 67 | 13 | 13 | 8 | 3 | 4.30 | .305 | 1.28 | 8.6 | 3.0 | 8.3 | 83.2 | 79 | 46 | 40 | 13 | 28 | 77 | 1 | 0 | 0 | 0 | 6 | 3 | 3 | 4.30 |
| SP | Carrasco, C.Carrasco, Carlos # >> | 27 | 2014 | R | 47 | 13 | 13 | 0 | 3 | 4.91 | .338 | 1.53 | 10.0 | 4.0 | 8.4 | 47.2 | 52 | 26 | 26 | 5 | 21 | 44 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 3.85 |
| SP | Clevinger, M.Clevinger, Mike >> | 28 | 2019 | R | 42 | 13 | 13 | 7 | 2 | 3.73 | .319 | 1.39 | 8.1 | 4.6 | 8.9 | 79.2 | 71 | 38 | 33 | 10 | 40 | 78 | 1 | 0 | 0 | 0 | 7 | 1 | 0 | 4.23 |
| RP | Perez, O.Perez, Oliver >> | 37 | 2018 | L | 97 | 38 | 0 | 4 | 3 | 3.22 | .287 | 1.21 | 7.0 | 4.1 | 9.4 | 44.2 | 34 | 16 | 16 | 4 | 20 | 46 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 3.45 |
| RP | Manship, J.Manship, Jeff >> | 30 | 2015 | R | 91 | 39 | 0 | 7 | 0 | 3.22 | .268 | 1.07 | 7.2 | 2.7 | 6.8 | 44.2 | 35 | 16 | 16 | 4 | 13 | 33 | 0 | 8 | 2 | 0 | 0 | 1 | 0 | 3.64 |
| RP | Gaddis, H.Gaddis, Hunter >> | 26 | 2024 | R | 85 | 18 | 0 | 1 | 1 | 3.75 | .327 | 1.46 | 9.4 | 3.8 | 7.1 | 24.0 | 25 | 10 | 10 | 1 | 10 | 19 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 3.21 |
| RP | Clippard, T.Clippard, Tyler >> | 34 | 2019 | R | 69 | 19 | 0 | 1 | 2 | 2.52 | .286 | 1.16 | 7.6 | 2.9 | 9.0 | 25.0 | 21 | 8 | 7 | 3 | 8 | 25 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.64 |
| RP | Cabrera, F.Cabrera, Fernando >> | 25 | 2006 | R | 12 | 15 | 0 | 0 | 3 | 7.13 | .376 | 1.81 | 12.2 | 4.8 | 8.5 | 17.2 | 23 | 14 | 14 | 4 | 9 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.76 |