| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 32 | 32 | 13 | 14 | 3.26 | .258 | 1.02 | 7.6 | 1.6 | 5.9 | 229.1 | 194 | 94 | 83 | 34 | 41 | 151 | 9 | 0 | 0 | 3 | 21 | 4 | 6 | 4.20 |
| SP | Mathewson, C.Mathewson, Christy # >> | 29 | 1909 | R | 87 | 31 | 31 | 16 | 9 | 3.19 | .275 | 1.10 | 8.0 | 2.0 | 5.0 | 205.2 | 182 | 86 | 73 | 18 | 45 | 115 | 4 | 0 | 0 | 2 | 22 | 7 | 0 | 3.78 |
| SP | Perritt, P.Perritt, Pol >> | 26 | 1917 | R | 36 | 31 | 31 | 9 | 12 | 5.71 | .329 | 1.44 | 11.2 | 1.9 | 5.7 | 160.2 | 199 | 116 | 102 | 27 | 33 | 101 | 1 | 0 | 0 | 0 | 14 | 4 | 3 | 4.63 |
| SP | Samardzija, J.Samardzija, Jeff >> | 34 | 2019 | R | 37 | 30 | 30 | 6 | 15 | 5.40 | .343 | 1.54 | 10.2 | 3.7 | 6.0 | 148.1 | 168 | 97 | 89 | 23 | 61 | 99 | 0 | 0 | 0 | 0 | 8 | 3 | 1 | 4.98 |
| SP | Barnes, J.Barnes, Jesse >> | 28 | 1920 | R | 27 | 29 | 29 | 11 | 8 | 4.39 | .318 | 1.39 | 9.7 | 2.8 | 5.3 | 178.1 | 192 | 106 | 87 | 15 | 55 | 104 | 1 | 0 | 0 | 0 | 19 | 2 | 2 | 3.89 |
| SU | Casilla, S.Casilla, Santiago >> | 34 | 2014 | R | 78 | 64 | 0 | 1 | 2 | 3.48 | .279 | 1.16 | 7.9 | 2.6 | 5.5 | 67.1 | 59 | 29 | 26 | 6 | 19 | 41 | 0 | 3 | 4 | 0 | 0 | 0 | 2 | 3.79 |
| CL | Jackson, M.Jackson, Mike † >> | 30 | 1994 | R | 93 | 64 | 0 | 2 | 2 | 4.02 | .331 | 1.48 | 8.4 | 5.1 | 9.4 | 62.2 | 58 | 30 | 28 | 5 | 35 | 65 | 0 | 40 | 6 | 0 | 0 | 0 | 0 | 3.65 |
| RP | Kontos, G.Kontos, George >> | 30 | 2015 | R | 35 | 74 | 0 | 5 | 9 | 4.73 | .336 | 1.49 | 10.6 | 2.8 | 4.5 | 93.1 | 110 | 63 | 49 | 16 | 29 | 46 | 0 | 2 | 2 | 0 | 0 | 3 | 4 | 5.28 |
| RP | Lopez, J.Lopez, Javier >> | 38 | 2015 | L | 81 | 47 | 0 | 6 | 1 | 4.10 | .270 | 1.11 | 6.3 | 3.8 | 3.7 | 59.1 | 41 | 33 | 27 | 3 | 25 | 24 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.12 |
| RP | Mota, G.Mota, Guillermo >> | 38 | 2011 | R | 22 | 34 | 0 | 1 | 0 | 4.97 | .359 | 1.63 | 8.8 | 6.1 | 5.9 | 41.2 | 40 | 24 | 23 | 5 | 28 | 27 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 5.46 |