| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 15 | 15 | 9 | 3 | 3.28 | .294 | 1.22 | 8.7 | 2.4 | 8.1 | 109.2 | 105 | 41 | 40 | 8 | 29 | 98 | 4 | 0 | 0 | 0 | 10 | 3 | 1 | 3.04 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 15 | 15 | 8 | 3 | 3.17 | .298 | 1.25 | 7.0 | 4.3 | 7.8 | 88.0 | 68 | 31 | 31 | 10 | 42 | 76 | 0 | 0 | 0 | 0 | 9 | 2 | 2 | 4.25 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 15 | 15 | 8 | 3 | 2.61 | .253 | 1.00 | 6.5 | 2.5 | 4.6 | 124.0 | 89 | 41 | 36 | 9 | 35 | 64 | 7 | 0 | 0 | 1 | 11 | 2 | 0 | 3.81 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 14 | 14 | 4 | 4 | 5.54 | .324 | 1.43 | 10.7 | 2.3 | 7.8 | 76.1 | 90 | 50 | 47 | 14 | 19 | 66 | 0 | 0 | 0 | 0 | 6 | 1 | 1 | 4.45 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 37 | 0 | 4 | 4 | 4.00 | .297 | 1.24 | 7.2 | 4.0 | 8.6 | 45.0 | 36 | 21 | 20 | 6 | 20 | 43 | 0 | 7 | 1 | 0 | 0 | 1 | 3 | 4.22 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 30 | 0 | 3 | 1 | 3.35 | .289 | 1.22 | 9.5 | 1.7 | 9.7 | 37.2 | 39 | 16 | 14 | 3 | 7 | 40 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.46 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 6 | 0 | 1 | 0 | 2.70 | .231 | 0.90 | 7.5 | 1.5 | 9.0 | 6.2 | 5 | 2 | 2 | 1 | 1 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.67 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 7 | 0 | 0 | 1 | 7.94 | .292 | 1.24 | 10.8 | 1.8 | 10.8 | 5.2 | 6 | 5 | 5 | 3 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.00 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 8 | 0 | 0 | 0 | 5.19 | .395 | 1.96 | 5.6 | 13.5 | 12.4 | 8.2 | 5 | 5 | 5 | 1 | 12 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.38 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 8 | 0 | 2 | 0 | 4.58 | .325 | 1.44 | 8.2 | 4.9 | 8.7 | 35.1 | 32 | 18 | 18 | 1 | 19 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.06 |