| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 15 | 15 | 6 | 5 | 2.82 | .259 | 1.04 | 7.0 | 2.4 | 9.2 | 108.2 | 84 | 34 | 34 | 15 | 29 | 110 | 1 | 0 | 0 | 0 | 11 | 1 | 0 | 3.60 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 15 | 15 | 5 | 8 | 4.37 | .308 | 1.33 | 10.1 | 1.9 | 5.4 | 111.1 | 124 | 58 | 54 | 11 | 24 | 66 | 4 | 0 | 0 | 0 | 8 | 1 | 1 | 3.77 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 15 | 15 | 6 | 6 | 3.78 | .285 | 1.18 | 7.9 | 2.7 | 7.1 | 126.1 | 111 | 55 | 53 | 13 | 38 | 99 | 5 | 0 | 0 | 0 | 10 | 2 | 3 | 3.72 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 39 | 0 | 2 | 2 | 4.50 | .355 | 1.59 | 8.0 | 6.3 | 11.3 | 46.0 | 41 | 26 | 23 | 6 | 32 | 58 | 0 | 6 | 1 | 0 | 0 | 3 | 4 | 4.46 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 28 | 0 | 2 | 3 | 5.67 | .310 | 1.35 | 9.0 | 3.3 | 12.5 | 33.1 | 33 | 22 | 21 | 7 | 12 | 46 | 0 | 3 | 5 | 0 | 0 | 0 | 2 | 4.06 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 21 | 0 | 2 | 0 | 5.09 | .384 | 1.81 | 11.1 | 5.8 | 11.1 | 17.2 | 21 | 12 | 10 | 3 | 11 | 21 | 0 | 1 | 0 | 0 | 0 | 1 | 4 | 4.94 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 15 | 0 | 1 | 1 | 3.10 | .265 | 1.03 | 6.8 | 2.7 | 8.6 | 20.1 | 15 | 9 | 7 | 3 | 6 | 19 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.10 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 2 | 2 | 2 | 0 | 3.55 | .321 | 1.34 | 7.5 | 5.3 | 6.0 | 12.2 | 10 | 5 | 5 | 2 | 7 | 8 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 5.83 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 54 | 13 | 0 | 2 | 3 | 6.46 | .403 | 2.02 | 14.4 | 4.2 | 8.4 | 15.1 | 24 | 11 | 11 | 5 | 7 | 14 | 0 | 4 | 3 | 0 | 0 | 0 | 1 | 6.87 |