| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 37 | 37 | 14 | 19 | 4.38 | .290 | 1.20 | 7.7 | 3.2 | 7.8 | 244.1 | 208 | 122 | 119 | 33 | 86 | 211 | 4 | 0 | 0 | 2 | 17 | 5 | 5 | 4.15 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 33 | 33 | 12 | 12 | 4.00 | .313 | 1.35 | 9.3 | 2.8 | 5.1 | 231.2 | 239 | 112 | 103 | 25 | 73 | 131 | 2 | 0 | 0 | 0 | 21 | 5 | 5 | 4.29 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 67 | 0 | 1 | 1 | 3.25 | .312 | 1.36 | 8.4 | 3.8 | 8.9 | 61.0 | 57 | 22 | 22 | 2 | 26 | 60 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.74 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 66 | 0 | 10 | 8 | 4.05 | .310 | 1.35 | 8.2 | 4.1 | 9.7 | 66.2 | 60 | 30 | 30 | 9 | 30 | 71 | 0 | 37 | 6 | 0 | 0 | 0 | 5 | 3.98 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 77 | 0 | 3 | 1 | 2.66 | .253 | 0.97 | 5.6 | 3.1 | 6.9 | 61.0 | 38 | 18 | 18 | 3 | 21 | 47 | 0 | 2 | 0 | 0 | 0 | 3 | 4 | 3.28 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 51 | 0 | 8 | 1 | 5.65 | .317 | 1.37 | 9.7 | 2.6 | 8.6 | 51.0 | 55 | 33 | 32 | 10 | 15 | 49 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 4.57 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Seaver, T.Seaver, Tom $ >> | 27 | 1971 | R | 71 | 2 | 0 | 0 | 0 | 0.00 | .286 | 1.20 | 0.0 | 18.0 | 9.0 | 1.2 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.00 |