| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 93 | 36 | 36 | 20 | 11 | 2.71 | .271 | 1.10 | 7.0 | 2.9 | 7.0 | 272.2 | 211 | 87 | 82 | 17 | 89 | 212 | 7 | 0 | 0 | 0 | 25 | 4 | 6 | 3.28 |
| SP | Mathewson, C.Mathewson, Christy # $ >> | 28 | 1908 | R | 83 | 33 | 33 | 20 | 10 | 3.06 | .263 | 1.05 | 7.6 | 1.9 | 5.2 | 252.2 | 213 | 89 | 86 | 13 | 52 | 145 | 9 | 0 | 0 | 5 | 23 | 5 | 3 | 3.20 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 6 | 6 | 4 | 2 | 3.15 | .271 | 1.09 | 8.0 | 2.0 | 8.0 | 45.2 | 40 | 16 | 16 | 6 | 10 | 40 | 2 | 0 | 0 | 1 | 4 | 1 | 2 | 3.69 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 85 | 0 | 5 | 6 | 4.09 | .295 | 1.24 | 6.2 | 5.0 | 7.6 | 101.1 | 70 | 46 | 46 | 10 | 56 | 85 | 0 | 12 | 2 | 0 | 0 | 1 | 7 | 4.30 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 60 | 61 | 0 | 5 | 2 | 2.43 | .272 | 1.11 | 6.4 | 3.6 | 3.5 | 70.1 | 50 | 20 | 19 | 7 | 28 | 27 | 0 | 13 | 1 | 0 | 0 | 1 | 2 | 4.77 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 42 | 0 | 1 | 1 | 1.43 | .237 | 0.91 | 5.4 | 2.9 | 9.5 | 50.1 | 30 | 9 | 8 | 2 | 16 | 53 | 0 | 7 | 0 | 0 | 0 | 1 | 0 | 2.42 |
| SP | Maddux, G.Maddux, Greg $ >> | 29 | 1995 | R | 89 | 31 | 30 | 8 | 17 | 4.39 | .295 | 1.24 | 9.2 | 1.9 | 4.7 | 223.1 | 229 | 116 | 109 | 29 | 47 | 117 | 10 | 0 | 0 | 1 | 12 | 4 | 0 | 4.33 |
| RP | Eichhorn, M.Eichhorn, Mark # >> | 26 | 1986 | R | 48 | 30 | 0 | 2 | 4 | 5.95 | .335 | 1.51 | 10.7 | 3.0 | 7.3 | 42.1 | 50 | 30 | 28 | 6 | 14 | 34 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.24 |
| SP | Harden, R.Harden, Rich # >> | 27 | 2008 | R | 60 | 30 | 28 | 6 | 12 | 5.02 | .331 | 1.48 | 8.7 | 4.6 | 7.7 | 165.0 | 159 | 96 | 92 | 22 | 85 | 141 | 0 | 0 | 0 | 0 | 11 | 1 | 3 | 4.59 |