| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 31 | 31 | 13 | 11 | 3.33 | .294 | 1.23 | 7.8 | 3.3 | 8.5 | 205.2 | 177 | 85 | 76 | 24 | 76 | 194 | 0 | 0 | 0 | 0 | 20 | 4 | 3 | 3.80 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 30 | 30 | 9 | 11 | 5.58 | .326 | 1.44 | 10.4 | 2.6 | 8.2 | 163.0 | 188 | 104 | 101 | 19 | 47 | 149 | 2 | 0 | 0 | 1 | 12 | 2 | 8 | 3.59 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 29 | 29 | 12 | 9 | 4.22 | .285 | 1.20 | 8.7 | 2.1 | 5.1 | 189.2 | 182 | 92 | 89 | 23 | 45 | 108 | 3 | 0 | 0 | 0 | 16 | 0 | 5 | 4.15 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 69 | 0 | 11 | 4 | 3.31 | .313 | 1.36 | 8.9 | 3.4 | 9.0 | 92.1 | 91 | 42 | 34 | 3 | 35 | 92 | 0 | 1 | 1 | 0 | 0 | 0 | 6 | 2.57 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 62 | 0 | 7 | 2 | 3.74 | .293 | 1.22 | 6.2 | 4.9 | 8.4 | 74.2 | 51 | 33 | 31 | 9 | 40 | 69 | 0 | 2 | 0 | 0 | 0 | 2 | 2 | 4.42 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 59 | 0 | 2 | 2 | 4.24 | .309 | 1.33 | 8.4 | 3.6 | 5.9 | 80.2 | 75 | 39 | 38 | 11 | 32 | 52 | 0 | 3 | 3 | 0 | 0 | 1 | 4 | 4.73 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 38 | 0 | 1 | 1 | 2.97 | .326 | 1.37 | 5.8 | 6.7 | 9.2 | 39.1 | 25 | 18 | 13 | 4 | 29 | 40 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 4.74 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 5 | 0 | 1 | 0 | 0.00 | .293 | 1.24 | 7.0 | 5.0 | 5.0 | 9.2 | 7 | 0 | 0 | 0 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.56 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 19 | 0 | 1 | 4 | 6.62 | .360 | 1.66 | 11.4 | 3.6 | 4.9 | 70.2 | 89 | 60 | 52 | 15 | 28 | 38 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 5.99 |