| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 32 | 32 | 14 | 10 | 3.98 | .289 | 1.20 | 8.5 | 2.4 | 9.1 | 199.0 | 187 | 91 | 88 | 23 | 52 | 201 | 0 | 0 | 0 | 0 | 20 | 4 | 0 | 3.33 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 31 | 31 | 12 | 9 | 5.64 | .346 | 1.57 | 10.1 | 4.0 | 6.2 | 169.0 | 190 | 110 | 106 | 23 | 75 | 117 | 0 | 0 | 0 | 0 | 14 | 3 | 2 | 4.77 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 71 | 30 | 30 | 13 | 12 | 4.84 | .315 | 1.38 | 9.6 | 2.9 | 4.8 | 191.2 | 203 | 110 | 103 | 16 | 62 | 102 | 6 | 0 | 0 | 3 | 14 | 0 | 5 | 3.99 |
| RP | Betances, D.Betances, Dellin † >> | 26 | 2014 | R | 94 | 91 | 0 | 6 | 3 | 3.57 | .306 | 1.31 | 7.0 | 4.9 | 8.3 | 90.2 | 70 | 38 | 36 | 6 | 49 | 83 | 0 | 5 | 3 | 0 | 0 | 1 | 6 | 3.69 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 68 | 0 | 2 | 1 | 2.80 | .269 | 1.10 | 8.3 | 1.7 | 8.0 | 64.1 | 59 | 21 | 20 | 7 | 12 | 57 | 0 | 8 | 1 | 0 | 0 | 0 | 0 | 3.20 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 36 | 0 | 5 | 0 | 2.10 | .270 | 1.08 | 7.1 | 2.6 | 7.7 | 34.1 | 27 | 8 | 8 | 1 | 10 | 29 | 0 | 1 | 0 | 0 | 0 | 1 | 3 | 2.65 |
| RP | Britton, Z.Britton, Zach # >> | 28 | 2016 | L | 78 | 84 | 0 | 4 | 4 | 4.74 | .288 | 1.21 | 6.9 | 4.1 | 9.5 | 68.1 | 52 | 39 | 36 | 10 | 31 | 72 | 0 | 3 | 5 | 0 | 0 | 0 | 3 | 4.16 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 70 | 21 | 0 | 3 | 1 | 3.32 | .345 | 1.53 | 5.7 | 8.1 | 9.9 | 19.0 | 12 | 7 | 7 | 2 | 17 | 21 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 5.00 |