| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 32 | 32 | 9 | 10 | 3.04 | .266 | 1.08 | 6.8 | 3.0 | 8.4 | 198.2 | 149 | 71 | 67 | 11 | 65 | 185 | 2 | 0 | 0 | 0 | 23 | 2 | 9 | 2.87 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 31 | 31 | 14 | 9 | 3.61 | .301 | 1.25 | 7.7 | 3.6 | 4.8 | 194.2 | 167 | 79 | 78 | 14 | 77 | 103 | 2 | 0 | 0 | 1 | 19 | 7 | 3 | 4.18 |
| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 94 | 31 | 31 | 15 | 10 | 3.29 | .284 | 1.15 | 7.5 | 2.8 | 5.4 | 200.0 | 167 | 75 | 73 | 18 | 63 | 121 | 4 | 0 | 0 | 1 | 18 | 8 | 3 | 4.03 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 77 | 31 | 30 | 12 | 12 | 5.02 | .299 | 1.27 | 8.3 | 3.1 | 5.2 | 177.2 | 164 | 105 | 99 | 20 | 61 | 103 | 7 | 0 | 0 | 3 | 11 | 2 | 3 | 4.37 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 75 | 0 | 4 | 3 | 3.86 | .280 | 1.13 | 6.3 | 3.9 | 8.1 | 84.0 | 59 | 36 | 36 | 6 | 36 | 76 | 0 | 11 | 8 | 0 | 0 | 3 | 2 | 3.51 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 47 | 0 | 5 | 2 | 4.35 | .329 | 1.45 | 8.8 | 4.4 | 11.4 | 49.2 | 48 | 24 | 24 | 9 | 24 | 62 | 0 | 6 | 0 | 0 | 0 | 1 | 1 | 4.39 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 33 | 0 | 5 | 0 | 3.16 | .311 | 1.32 | 8.5 | 3.4 | 6.8 | 37.0 | 35 | 13 | 13 | 1 | 14 | 28 | 0 | 4 | 1 | 0 | 0 | 1 | 3 | 3.05 |
| RP | Radatz, D.Radatz, Dick >> | 27 | 1964 | R | 37 | 10 | 0 | 1 | 0 | 6.98 | .363 | 1.71 | 10.9 | 4.7 | 8.1 | 19.1 | 23 | 15 | 15 | 5 | 10 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.21 |