| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 32 | 32 | 8 | 11 | 4.05 | .301 | 1.26 | 7.6 | 3.7 | 7.6 | 184.2 | 156 | 88 | 83 | 19 | 76 | 155 | 1 | 0 | 0 | 0 | 17 | 6 | 3 | 3.99 |
| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 89 | 30 | 30 | 15 | 11 | 3.10 | .270 | 1.09 | 7.7 | 2.1 | 5.2 | 223.2 | 191 | 83 | 77 | 17 | 53 | 128 | 12 | 0 | 0 | 4 | 19 | 4 | 1 | 3.61 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 31 | 31 | 10 | 17 | 4.60 | .319 | 1.39 | 8.9 | 3.7 | 6.5 | 197.2 | 194 | 110 | 101 | 30 | 81 | 143 | 5 | 0 | 0 | 0 | 15 | 3 | 1 | 4.81 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 29 | 28 | 12 | 10 | 3.95 | .300 | 1.27 | 7.2 | 4.3 | 8.7 | 177.2 | 141 | 85 | 78 | 17 | 85 | 171 | 0 | 0 | 0 | 0 | 18 | 2 | 6 | 3.79 |
| RP | Betances, D.Betances, Dellin † >> | 26 | 2014 | R | 94 | 80 | 0 | 7 | 1 | 2.71 | .290 | 1.22 | 6.7 | 4.3 | 9.1 | 93.0 | 69 | 28 | 28 | 7 | 44 | 94 | 0 | 5 | 3 | 0 | 0 | 1 | 2 | 3.41 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 64 | 0 | 4 | 2 | 2.64 | .300 | 1.26 | 6.7 | 4.7 | 8.4 | 71.2 | 53 | 25 | 21 | 5 | 37 | 66 | 0 | 5 | 3 | 0 | 0 | 2 | 1 | 3.70 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 56 | 0 | 1 | 2 | 2.95 | .260 | 1.05 | 7.3 | 2.2 | 8.4 | 58.0 | 47 | 21 | 19 | 6 | 14 | 54 | 0 | 5 | 1 | 0 | 0 | 0 | 1 | 3.21 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 40 | 0 | 2 | 3 | 3.11 | .323 | 1.41 | 8.5 | 4.4 | 7.5 | 37.2 | 35 | 13 | 13 | 1 | 18 | 31 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.22 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 29 | 0 | 1 | 1 | 3.42 | .295 | 1.25 | 7.3 | 4.2 | 4.8 | 26.1 | 21 | 10 | 10 | 2 | 12 | 14 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 4.31 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 74 | 0 | 3 | 3 | 1.93 | .243 | 0.94 | 6.3 | 2.3 | 6.5 | 46.2 | 32 | 11 | 10 | 1 | 12 | 33 | 0 | 10 | 3 | 0 | 0 | 1 | 2 | 2.70 |
| RP | Rocker, J.Rocker, John >> | 25 | 1999 | L | 30 | 41 | 0 | 2 | 2 | 4.89 | .344 | 1.54 | 7.7 | 6.2 | 9.5 | 35.0 | 30 | 21 | 19 | 3 | 24 | 37 | 0 | 2 | 1 | 0 | 0 | 1 | 2 | 4.14 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 8 | 1 | 3 | 0 | 3.47 | .340 | 1.52 | 7.6 | 6.3 | 3.3 | 46.2 | 39 | 18 | 18 | 1 | 32 | 17 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 4.70 |