| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 30 | 30 | 19 | 7 | 3.97 | .307 | 1.30 | 8.5 | 3.2 | 4.8 | 192.2 | 182 | 87 | 85 | 16 | 68 | 102 | 2 | 0 | 0 | 0 | 19 | 6 | 3 | 4.18 |
| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 31 | 31 | 12 | 6 | 3.77 | .296 | 1.24 | 8.9 | 2.3 | 5.2 | 214.2 | 212 | 97 | 90 | 16 | 55 | 123 | 7 | 0 | 0 | 2 | 16 | 4 | 7 | 3.65 |
| SP | Waddell, R.Waddell, Rube # >> | 29 | 1905 | L | 67 | 31 | 31 | 7 | 11 | 4.98 | .336 | 1.50 | 10.1 | 3.4 | 5.3 | 141.0 | 159 | 83 | 78 | 26 | 53 | 83 | 0 | 0 | 0 | 0 | 12 | 2 | 1 | 5.39 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 78 | 0 | 12 | 4 | 3.48 | .284 | 1.17 | 7.6 | 2.9 | 8.0 | 106.0 | 90 | 45 | 41 | 7 | 34 | 94 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.10 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 53 | 0 | 5 | 2 | 2.48 | .237 | 0.92 | 5.6 | 2.7 | 6.8 | 76.1 | 47 | 22 | 21 | 7 | 23 | 57 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.64 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 54 | 0 | 0 | 3 | 2.73 | .299 | 1.28 | 8.7 | 2.9 | 7.5 | 59.1 | 57 | 21 | 18 | 6 | 19 | 49 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 3.63 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 65 | 0 | 1 | 3 | 2.30 | .264 | 1.06 | 7.2 | 2.4 | 8.3 | 74.1 | 59 | 19 | 19 | 6 | 20 | 68 | 0 | 37 | 4 | 0 | 0 | 1 | 1 | 3.07 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 22 | 2 | 3 | 3 | 4.24 | .346 | 1.54 | 11.3 | 2.7 | 4.9 | 46.2 | 58 | 22 | 22 | 4 | 14 | 25 | 0 | 2 | 0 | 0 | 1 | 2 | 0 | 4.09 |