| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 31 | 31 | 6 | 12 | 5.24 | .330 | 1.45 | 9.8 | 3.3 | 7.9 | 182.0 | 198 | 106 | 106 | 26 | 66 | 160 | 2 | 0 | 0 | 0 | 14 | 5 | 4 | 4.27 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 83 | 31 | 31 | 13 | 10 | 5.16 | .332 | 1.46 | 10.1 | 3.0 | 7.2 | 190.0 | 214 | 114 | 109 | 28 | 63 | 152 | 0 | 0 | 0 | 0 | 14 | 6 | 6 | 4.41 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 31 | 31 | 9 | 12 | 6.77 | .354 | 1.62 | 10.6 | 4.0 | 7.7 | 149.0 | 175 | 120 | 112 | 24 | 66 | 128 | 1 | 0 | 0 | 1 | 11 | 4 | 2 | 4.79 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 77 | 0 | 4 | 4 | 3.21 | .288 | 1.19 | 6.8 | 4.0 | 8.7 | 84.0 | 63 | 30 | 30 | 9 | 37 | 81 | 0 | 39 | 3 | 0 | 0 | 2 | 1 | 3.86 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 79 | 0 | 5 | 3 | 4.71 | .299 | 1.28 | 8.3 | 3.3 | 7.2 | 93.2 | 86 | 51 | 49 | 18 | 34 | 74 | 0 | 4 | 3 | 0 | 0 | 0 | 1 | 5.02 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 69 | 0 | 6 | 4 | 4.84 | .335 | 1.50 | 8.5 | 5.1 | 10.3 | 70.2 | 66 | 46 | 38 | 9 | 40 | 80 | 0 | 1 | 3 | 0 | 0 | 1 | 3 | 4.14 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 53 | 0 | 4 | 0 | 2.20 | .219 | 0.83 | 5.7 | 1.8 | 8.8 | 73.2 | 46 | 18 | 18 | 4 | 15 | 71 | 0 | 0 | 1 | 0 | 0 | 1 | 3 | 2.42 |