| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 16 | 16 | 4 | 7 | 4.08 | .299 | 1.27 | 9.6 | 2.0 | 5.1 | 114.2 | 121 | 58 | 52 | 12 | 25 | 65 | 3 | 0 | 0 | 0 | 10 | 1 | 1 | 3.91 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 83 | 15 | 15 | 6 | 7 | 4.39 | .320 | 1.39 | 9.1 | 3.5 | 7.6 | 104.2 | 105 | 56 | 51 | 8 | 41 | 88 | 1 | 0 | 0 | 0 | 6 | 2 | 4 | 3.55 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 15 | 15 | 6 | 5 | 4.92 | .320 | 1.41 | 9.9 | 2.9 | 4.3 | 100.2 | 110 | 58 | 55 | 8 | 32 | 48 | 1 | 0 | 0 | 0 | 8 | 0 | 4 | 4.04 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 31 | 0 | 1 | 2 | 1.99 | .221 | 0.85 | 6.7 | 1.2 | 7.0 | 31.2 | 23 | 8 | 7 | 1 | 4 | 24 | 0 | 19 | 0 | 0 | 0 | 0 | 0 | 2.26 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 41 | 0 | 2 | 5 | 6.19 | .345 | 1.58 | 10.1 | 4.1 | 8.4 | 48.0 | 54 | 37 | 33 | 5 | 22 | 45 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.85 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 30 | 0 | 1 | 2 | 7.26 | .367 | 1.71 | 9.6 | 5.8 | 8.7 | 31.0 | 33 | 27 | 25 | 5 | 20 | 30 | 0 | 0 | 2 | 0 | 0 | 1 | 2 | 5.19 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 17 | 0 | 0 | 1 | 5.49 | .344 | 1.58 | 9.5 | 5.2 | 11.8 | 19.2 | 20 | 12 | 12 | 3 | 11 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.16 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 69 | 22 | 0 | 0 | 0 | 4.24 | .346 | 1.59 | 9.0 | 5.5 | 9.8 | 23.1 | 23 | 16 | 11 | 5 | 14 | 25 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.48 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 2 | 2 | 0 | 1 | 17.47 | .469 | 2.65 | 21.6 | 5.4 | 5.4 | 5.2 | 12 | 11 | 11 | 3 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.40 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 5 | 0 | 0 | 1 | 6.75 | .385 | 1.88 | 18.0 | 0.0 | 1.8 | 5.1 | 10 | 4 | 4 | 2 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.80 |