| SP | Tiant, L.Tiant, Luis # >> | 28 | 1968 | R | 97 | 34 | 34 | 10 | 16 | 3.99 | .301 | 1.27 | 8.5 | 2.9 | 7.6 | 241.1 | 228 | 112 | 107 | 29 | 78 | 204 | 6 | 0 | 0 | 0 | 18 | 6 | 3 | 3.92 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 80 | 33 | 33 | 9 | 18 | 4.70 | .302 | 1.27 | 8.6 | 2.8 | 4.7 | 220.0 | 211 | 121 | 115 | 21 | 69 | 116 | 8 | 0 | 0 | 3 | 15 | 6 | 2 | 4.21 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 66 | 32 | 32 | 11 | 14 | 5.37 | .338 | 1.51 | 9.5 | 4.1 | 4.8 | 199.1 | 210 | 132 | 119 | 26 | 91 | 106 | 4 | 0 | 0 | 0 | 12 | 5 | 3 | 5.08 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 62 | 31 | 31 | 6 | 13 | 5.81 | .346 | 1.57 | 10.1 | 4.0 | 4.6 | 182.2 | 205 | 121 | 118 | 23 | 81 | 93 | 0 | 0 | 0 | 0 | 11 | 4 | 1 | 5.02 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 84 | 0 | 7 | 3 | 2.68 | .272 | 1.10 | 6.2 | 3.7 | 9.2 | 114.1 | 79 | 38 | 34 | 6 | 47 | 116 | 0 | 8 | 6 | 0 | 0 | 2 | 0 | 2.94 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 75 | 0 | 5 | 4 | 3.71 | .267 | 1.07 | 7.1 | 2.5 | 8.1 | 97.0 | 77 | 41 | 40 | 16 | 27 | 87 | 0 | 8 | 5 | 0 | 0 | 2 | 3 | 4.25 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 58 | 0 | 4 | 3 | 3.86 | .307 | 1.29 | 7.5 | 4.1 | 7.7 | 70.0 | 58 | 32 | 30 | 11 | 32 | 60 | 0 | 9 | 1 | 0 | 0 | 3 | 2 | 4.83 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 52 | 0 | 4 | 4 | 4.73 | .349 | 1.59 | 8.8 | 5.5 | 8.2 | 59.0 | 58 | 33 | 31 | 3 | 36 | 54 | 0 | 3 | 1 | 0 | 0 | 1 | 8 | 3.71 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 57 | 1 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 18.0 | 1.1 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1.00 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 56 | 28 | 0 | 3 | 3 | 6.97 | .385 | 1.82 | 12.5 | 4.1 | 4.8 | 51.2 | 71 | 42 | 40 | 5 | 23 | 27 | 0 | 4 | 0 | 0 | 0 | 3 | 0 | 4.75 |