| SP | Reulbach, E.Reulbach, Ed † $$ >> | 24 | 1906 | R | 60 | 35 | 35 | 18 | 8 | 3.40 | .286 | 1.18 | 6.8 | 3.8 | 3.6 | 230.0 | 175 | 89 | 87 | 21 | 96 | 92 | 3 | 0 | 0 | 1 | 25 | 6 | 8 | 4.72 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 35 | 35 | 11 | 11 | 3.50 | .284 | 1.15 | 6.8 | 3.6 | 7.2 | 192.2 | 146 | 75 | 75 | 16 | 76 | 153 | 0 | 0 | 0 | 0 | 20 | 7 | 5 | 3.79 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 33 | 33 | 16 | 9 | 3.54 | .274 | 1.12 | 7.7 | 2.3 | 4.6 | 221.0 | 190 | 91 | 87 | 15 | 57 | 114 | 2 | 0 | 0 | 1 | 22 | 3 | 3 | 3.67 |
| RP | Doolittle, S.Doolittle, Sean $ >> | 31 | 2018 | L | 99 | 103 | 0 | 2 | 2 | 2.91 | .220 | 0.85 | 6.2 | 1.5 | 9.9 | 74.1 | 51 | 25 | 24 | 8 | 12 | 81 | 0 | 5 | 5 | 0 | 0 | 0 | 3 | 2.70 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 77 | 0 | 2 | 3 | 3.46 | .284 | 1.19 | 6.8 | 4.0 | 9.0 | 52.0 | 39 | 20 | 20 | 5 | 23 | 52 | 0 | 9 | 1 | 0 | 0 | 0 | 3 | 3.58 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 98 | 0 | 5 | 4 | 2.71 | .227 | 0.82 | 4.4 | 3.0 | 5.6 | 79.2 | 39 | 28 | 24 | 10 | 26 | 49 | 0 | 5 | 1 | 0 | 0 | 5 | 0 | 4.58 |
| RP | Brewer, J.Brewer, Jim $ >> | 35 | 1972 | L | 73 | 44 | 0 | 4 | 3 | 2.84 | .224 | 0.87 | 5.4 | 2.4 | 3.8 | 38.0 | 23 | 14 | 12 | 1 | 10 | 16 | 0 | 11 | 0 | 0 | 0 | 0 | 0 | 3.29 |
| RP | Messersmith, A.Messersmith, Andy # >> | 23 | 1968 | R | 57 | 77 | 0 | 1 | 3 | 4.97 | .356 | 1.66 | 8.6 | 6.5 | 8.6 | 50.2 | 48 | 29 | 28 | 6 | 36 | 48 | 0 | 5 | 5 | 0 | 0 | 0 | 1 | 4.80 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 31 | 28 | 0 | 2 | 1 | 3.48 | .306 | 1.32 | 5.8 | 6.1 | 9.0 | 31.0 | 20 | 12 | 12 | 6 | 21 | 31 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 5.55 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 59 | 0 | 1 | 4 | 3.88 | .287 | 1.21 | 7.8 | 3.1 | 5.4 | 58.0 | 50 | 26 | 25 | 10 | 20 | 35 | 0 | 2 | 5 | 0 | 0 | 0 | 4 | 5.07 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 75 | 33 | 25 | 10 | 10 | 4.71 | .329 | 1.44 | 9.3 | 3.7 | 4.1 | 172.0 | 177 | 94 | 90 | 21 | 71 | 78 | 2 | 0 | 0 | 0 | 12 | 5 | 1 | 5.01 |