| SP | Martinez, P.Martinez, Pedro † $$ >> | 29 | 2000 | R | 100 | 36 | 36 | 17 | 9 | 2.69 | .256 | 1.01 | 6.6 | 2.6 | 8.4 | 264.2 | 193 | 83 | 79 | 21 | 75 | 246 | 14 | 0 | 0 | 5 | 25 | 5 | 7 | 3.08 |
| SP | Arrieta, J.Arrieta, Jake † # >> | 29 | 2015 | R | 92 | 35 | 35 | 18 | 6 | 3.13 | .280 | 1.15 | 7.2 | 3.1 | 8.1 | 233.0 | 187 | 85 | 81 | 16 | 80 | 209 | 5 | 0 | 0 | 4 | 22 | 5 | 3 | 3.19 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 34 | 34 | 17 | 10 | 3.27 | .293 | 1.23 | 7.2 | 3.9 | 4.5 | 225.2 | 179 | 89 | 82 | 13 | 98 | 112 | 3 | 0 | 0 | 0 | 22 | 4 | 4 | 4.12 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 102 | 0 | 4 | 0 | 2.86 | .258 | 1.05 | 6.3 | 3.1 | 9.4 | 66.0 | 46 | 21 | 21 | 5 | 23 | 69 | 0 | 6 | 2 | 0 | 0 | 0 | 2 | 2.94 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 65 | 0 | 1 | 2 | 4.62 | .311 | 1.35 | 8.5 | 3.6 | 7.8 | 37.0 | 35 | 19 | 19 | 6 | 15 | 32 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 4.59 |
| RP | Brewer, J.Brewer, Jim $ >> | 35 | 1972 | L | 73 | 68 | 0 | 5 | 1 | 3.94 | .294 | 1.23 | 7.8 | 3.4 | 6.6 | 45.2 | 39 | 21 | 20 | 1 | 17 | 33 | 0 | 11 | 3 | 0 | 0 | 1 | 4 | 3.02 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 38 | 0 | 5 | 3 | 2.70 | .292 | 1.24 | 6.9 | 4.5 | 11.8 | 26.2 | 20 | 9 | 8 | 4 | 13 | 34 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 3.88 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 33 | 41 | 0 | 1 | 4 | 2.70 | .333 | 1.47 | 7.4 | 6.0 | 6.3 | 33.1 | 27 | 10 | 10 | 2 | 22 | 23 | 0 | 10 | 3 | 0 | 0 | 1 | 0 | 4.48 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 32 | 0 | 2 | 3 | 5.21 | .324 | 1.44 | 8.2 | 4.9 | 5.1 | 46.2 | 42 | 27 | 27 | 3 | 25 | 26 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 4.35 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 36 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 29 | 0 | 9 | 0 | 3.58 | .279 | 1.16 | 6.9 | 3.6 | 7.6 | 100.2 | 77 | 40 | 40 | 7 | 40 | 84 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.43 |