| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 36 | 36 | 20 | 7 | 3.26 | .281 | 1.15 | 7.2 | 3.1 | 9.2 | 218.1 | 175 | 80 | 79 | 18 | 76 | 223 | 0 | 0 | 0 | 0 | 26 | 5 | 0 | 3.14 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 89 | 35 | 35 | 10 | 13 | 5.18 | .327 | 1.44 | 9.9 | 3.2 | 9.0 | 199.2 | 218 | 119 | 115 | 29 | 70 | 200 | 3 | 0 | 0 | 1 | 14 | 3 | 5 | 3.98 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 32 | 31 | 11 | 14 | 6.03 | .332 | 1.46 | 11.2 | 1.9 | 4.6 | 173.0 | 215 | 135 | 116 | 22 | 37 | 88 | 3 | 0 | 0 | 0 | 10 | 6 | 2 | 4.38 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 82 | 0 | 4 | 6 | 2.08 | .265 | 1.07 | 6.2 | 3.5 | 11.1 | 99.2 | 68 | 26 | 23 | 5 | 39 | 122 | 0 | 32 | 2 | 0 | 0 | 1 | 6 | 2.40 |
| RP | Davis, W.Davis, Wade # >> | 29 | 2015 | R | 89 | 95 | 0 | 7 | 1 | 4.17 | .288 | 1.18 | 6.7 | 3.9 | 7.4 | 112.1 | 83 | 64 | 52 | 10 | 49 | 92 | 0 | 4 | 2 | 0 | 0 | 4 | 2 | 3.94 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 79 | 0 | 2 | 3 | 4.57 | .309 | 1.33 | 7.4 | 4.6 | 9.4 | 86.2 | 71 | 46 | 44 | 11 | 44 | 90 | 0 | 1 | 2 | 0 | 0 | 1 | 4 | 4.14 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 75 | 0 | 8 | 4 | 5.81 | .345 | 1.54 | 10.8 | 3.0 | 8.5 | 93.0 | 112 | 60 | 60 | 17 | 31 | 88 | 0 | 2 | 1 | 0 | 0 | 4 | 3 | 4.61 |