| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 25 | 25 | 8 | 11 | 3.87 | .279 | 1.12 | 7.5 | 2.6 | 7.1 | 153.1 | 128 | 67 | 66 | 21 | 44 | 121 | 1 | 0 | 0 | 0 | 18 | 6 | 3 | 4.18 |
| SP | Leonard, D.Leonard, Dutch † >> | 22 | 1914 | L | 91 | 25 | 25 | 9 | 3 | 2.50 | .238 | 0.92 | 5.2 | 3.1 | 4.9 | 169.0 | 98 | 48 | 47 | 10 | 58 | 92 | 2 | 0 | 0 | 2 | 17 | 2 | 2 | 3.75 |
| SP | Mathewson, C.Mathewson, Christy >> | 29 | 1909 | R | 85 | 24 | 24 | 12 | 7 | 3.20 | .287 | 1.17 | 8.0 | 2.6 | 4.4 | 157.1 | 139 | 60 | 56 | 9 | 45 | 76 | 2 | 0 | 0 | 1 | 16 | 6 | 2 | 3.75 |
| SP | Alexander, P.Alexander, Pete † # >> | 28 | 1915 | R | 88 | 24 | 24 | 14 | 9 | 3.41 | .266 | 1.06 | 7.3 | 2.2 | 4.5 | 169.0 | 137 | 70 | 64 | 12 | 42 | 85 | 7 | 0 | 0 | 1 | 19 | 5 | 5 | 3.75 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 21 | 21 | 7 | 9 | 5.03 | .312 | 1.35 | 8.8 | 3.3 | 7.0 | 116.1 | 114 | 70 | 65 | 13 | 43 | 90 | 1 | 0 | 0 | 0 | 10 | 1 | 5 | 4.04 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 68 | 0 | 3 | 4 | 2.50 | .217 | 0.82 | 5.6 | 1.8 | 7.4 | 90.0 | 56 | 28 | 25 | 8 | 18 | 74 | 0 | 11 | 1 | 0 | 0 | 1 | 2 | 3.14 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 18 | 0 | 0 | 2 | 3.86 | .291 | 1.23 | 7.0 | 4.5 | 11.0 | 18.2 | 14 | 8 | 8 | 1 | 9 | 22 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.78 |