| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 27 | 27 | 11 | 9 | 4.76 | .326 | 1.43 | 9.2 | 3.6 | 6.8 | 168.1 | 172 | 92 | 89 | 15 | 68 | 127 | 2 | 0 | 0 | 0 | 13 | 4 | 9 | 3.93 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 26 | 26 | 10 | 12 | 4.05 | .284 | 1.17 | 9.1 | 1.5 | 5.0 | 175.2 | 176 | 86 | 79 | 22 | 30 | 98 | 3 | 0 | 0 | 1 | 10 | 3 | 4 | 4.08 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 26 | 26 | 12 | 10 | 5.15 | .319 | 1.38 | 9.2 | 3.3 | 7.4 | 150.1 | 153 | 88 | 86 | 25 | 55 | 124 | 2 | 0 | 0 | 0 | 12 | 3 | 3 | 4.67 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 24 | 24 | 8 | 7 | 4.56 | .296 | 1.24 | 9.2 | 2.0 | 6.7 | 128.1 | 131 | 70 | 65 | 25 | 28 | 95 | 1 | 0 | 0 | 0 | 12 | 3 | 4 | 4.78 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 74 | 0 | 4 | 5 | 3.21 | .276 | 1.14 | 7.8 | 2.5 | 9.0 | 53.1 | 46 | 19 | 19 | 6 | 15 | 53 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 3.32 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 45 | 0 | 4 | 2 | 3.14 | .328 | 1.43 | 10.6 | 2.6 | 6.8 | 28.2 | 33 | 12 | 10 | 2 | 8 | 21 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.39 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 31 | 0 | 4 | 1 | 4.22 | .340 | 1.55 | 10.3 | 3.9 | 6.0 | 21.1 | 24 | 11 | 10 | 4 | 9 | 14 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 5.43 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 17 | 0 | 2 | 2 | 4.05 | .344 | 1.58 | 10.4 | 4.2 | 8.3 | 13.1 | 15 | 6 | 6 | 0 | 6 | 12 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 2.54 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 72 | 0 | 1 | 1 | 4.83 | .267 | 1.09 | 7.4 | 2.5 | 11.5 | 50.1 | 41 | 28 | 27 | 9 | 14 | 64 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 3.62 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 51 | 0 | 1 | 2 | 2.88 | .309 | 1.34 | 7.9 | 4.2 | 8.2 | 34.1 | 30 | 11 | 11 | 2 | 16 | 31 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.35 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 24 | 0 | 0 | 0 | 5.16 | .320 | 1.37 | 11.0 | 1.6 | 8.6 | 22.2 | 27 | 15 | 13 | 3 | 4 | 21 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.55 |