| SP | Leonard, D.Leonard, Dutch † >> | 22 | 1914 | L | 91 | 28 | 28 | 9 | 6 | 2.79 | .264 | 1.07 | 7.3 | 2.4 | 5.9 | 161.1 | 130 | 51 | 50 | 9 | 43 | 105 | 0 | 0 | 0 | 0 | 14 | 1 | 3 | 3.24 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 26 | 26 | 12 | 2 | 3.51 | .319 | 1.34 | 7.1 | 5.0 | 4.1 | 159.0 | 125 | 66 | 62 | 12 | 88 | 73 | 0 | 0 | 0 | 0 | 14 | 10 | 5 | 4.91 |
| SP | Fernandez, S.Fernandez, Sid # >> | 23 | 1985 | L | 49 | 20 | 20 | 8 | 4 | 4.04 | .287 | 1.17 | 6.8 | 3.8 | 7.0 | 120.1 | 90 | 59 | 54 | 16 | 51 | 93 | 1 | 0 | 0 | 0 | 13 | 4 | 1 | 4.56 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 94 | 0 | 6 | 1 | 2.49 | .300 | 1.24 | 5.5 | 5.8 | 10.2 | 61.1 | 37 | 19 | 17 | 3 | 39 | 69 | 0 | 2 | 1 | 0 | 0 | 3 | 0 | 3.44 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 77 | 0 | 4 | 2 | 3.31 | .297 | 1.25 | 6.7 | 4.7 | 10.5 | 54.1 | 40 | 21 | 20 | 7 | 28 | 63 | 0 | 7 | 2 | 0 | 0 | 1 | 2 | 3.96 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 55 | 0 | 1 | 5 | 4.89 | .320 | 1.39 | 7.6 | 4.9 | 9.4 | 46.0 | 39 | 25 | 25 | 9 | 25 | 48 | 0 | 8 | 2 | 0 | 0 | 1 | 2 | 5.15 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 31 | 62 | 0 | 4 | 1 | 2.68 | .288 | 1.17 | 6.3 | 4.2 | 9.2 | 47.0 | 33 | 14 | 14 | 2 | 22 | 48 | 0 | 8 | 1 | 0 | 0 | 2 | 0 | 3.04 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 32 | 0 | 2 | 2 | 5.70 | .333 | 1.50 | 9.6 | 3.9 | 9.6 | 30.0 | 32 | 19 | 19 | 4 | 13 | 32 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.90 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 11 | 0 | 4 | 1 | 2.70 | .306 | 1.32 | 9.0 | 3.4 | 7.9 | 16.2 | 16 | 5 | 5 | 2 | 6 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.00 |