| SP | Leonard, D.Leonard, Dutch † >> | 22 | 1914 | L | 91 | 27 | 27 | 12 | 4 | 3.08 | .256 | 1.03 | 5.9 | 3.3 | 4.4 | 143.0 | 94 | 50 | 49 | 7 | 53 | 70 | 1 | 0 | 0 | 1 | 9 | 1 | 1 | 3.79 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 26 | 26 | 12 | 9 | 3.34 | .290 | 1.21 | 6.9 | 3.9 | 3.9 | 151.0 | 116 | 60 | 56 | 15 | 66 | 65 | 1 | 0 | 0 | 0 | 11 | 3 | 4 | 4.80 |
| SP | Fernandez, S.Fernandez, Sid † >> | 23 | 1985 | L | 49 | 26 | 26 | 16 | 5 | 2.87 | .263 | 1.05 | 6.2 | 3.3 | 7.3 | 150.1 | 103 | 53 | 48 | 13 | 55 | 122 | 0 | 0 | 0 | 0 | 16 | 3 | 2 | 3.66 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 24 | 24 | 10 | 7 | 3.81 | .301 | 1.28 | 7.0 | 4.6 | 3.3 | 148.2 | 115 | 66 | 63 | 11 | 75 | 55 | 2 | 0 | 0 | 1 | 15 | 2 | 0 | 4.78 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 81 | 0 | 5 | 3 | 3.65 | .303 | 1.31 | 7.1 | 4.8 | 10.0 | 56.2 | 44 | 24 | 23 | 6 | 30 | 62 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 3.79 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 74 | 0 | 2 | 0 | 2.30 | .278 | 1.13 | 4.5 | 5.8 | 8.2 | 54.2 | 27 | 15 | 14 | 0 | 35 | 49 | 0 | 4 | 0 | 0 | 0 | 1 | 2 | 3.19 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 51 | 0 | 2 | 0 | 2.52 | .241 | 0.95 | 4.6 | 4.1 | 7.5 | 35.2 | 18 | 10 | 10 | 4 | 16 | 29 | 0 | 11 | 1 | 0 | 0 | 0 | 0 | 4.20 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 70 | 0 | 5 | 2 | 2.45 | .279 | 1.16 | 7.0 | 3.5 | 7.8 | 44.0 | 34 | 12 | 12 | 0 | 17 | 38 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 2.43 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 33 | 52 | 0 | 2 | 1 | 1.43 | .280 | 1.17 | 6.1 | 4.6 | 8.5 | 37.2 | 25 | 7 | 6 | 0 | 19 | 35 | 0 | 9 | 1 | 0 | 0 | 0 | 0 | 2.65 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 38 | 0 | 3 | 0 | 2.51 | .271 | 1.07 | 5.7 | 4.0 | 10.0 | 43.0 | 27 | 13 | 12 | 4 | 19 | 48 | 0 | 5 | 1 | 0 | 0 | 2 | 1 | 3.44 |