| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 27 | 27 | 12 | 11 | 3.61 | .271 | 1.11 | 7.3 | 2.6 | 6.1 | 187.0 | 152 | 81 | 75 | 26 | 55 | 127 | 8 | 0 | 0 | 2 | 15 | 2 | 5 | 4.36 |
| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 92 | 26 | 26 | 12 | 8 | 3.36 | .295 | 1.23 | 9.3 | 1.9 | 7.3 | 179.2 | 184 | 72 | 67 | 18 | 37 | 145 | 2 | 0 | 0 | 2 | 19 | 5 | 5 | 3.39 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 73 | 0 | 4 | 5 | 3.59 | .269 | 1.09 | 7.2 | 2.6 | 8.9 | 85.1 | 68 | 36 | 34 | 13 | 25 | 84 | 0 | 4 | 3 | 0 | 0 | 1 | 1 | 3.93 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 53 | 0 | 3 | 3 | 3.03 | .271 | 1.10 | 6.9 | 3.0 | 9.4 | 65.1 | 50 | 24 | 22 | 3 | 22 | 68 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 2.57 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 53 | 0 | 1 | 3 | 4.53 | .324 | 1.42 | 9.0 | 3.9 | 9.3 | 53.2 | 53 | 27 | 27 | 8 | 23 | 55 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 4.25 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 86 | 0 | 2 | 2 | 3.98 | .332 | 1.44 | 6.6 | 6.3 | 12.4 | 61.0 | 45 | 29 | 27 | 8 | 43 | 84 | 0 | 2 | 1 | 0 | 0 | 3 | 2 | 4.21 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 43 | 0 | 1 | 1 | 6.18 | .337 | 1.50 | 10.4 | 3.2 | 9.0 | 39.1 | 45 | 27 | 27 | 9 | 14 | 39 | 0 | 4 | 3 | 0 | 0 | 1 | 0 | 5.15 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 15 | 0 | 1 | 1 | 6.75 | .414 | 2.12 | 16.0 | 3.7 | 4.9 | 22.2 | 39 | 20 | 17 | 5 | 9 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.09 |