| SP | Martinez, P.Martinez, Pedro † # >> | 29 | 2000 | R | 100 | 29 | 29 | 15 | 12 | 4.09 | .292 | 1.21 | 8.7 | 2.1 | 8.3 | 215.2 | 209 | 112 | 98 | 28 | 51 | 199 | 9 | 0 | 0 | 2 | 15 | 7 | 5 | 3.65 |
| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 28 | 28 | 9 | 12 | 4.62 | .309 | 1.32 | 9.0 | 2.9 | 5.4 | 208.1 | 208 | 119 | 107 | 30 | 67 | 125 | 5 | 0 | 0 | 0 | 13 | 4 | 2 | 4.70 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 27 | 27 | 4 | 11 | 6.09 | .340 | 1.52 | 10.2 | 3.5 | 5.4 | 139.0 | 157 | 97 | 94 | 26 | 54 | 84 | 0 | 0 | 0 | 0 | 8 | 4 | 3 | 5.47 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 73 | 0 | 2 | 4 | 5.22 | .316 | 1.34 | 8.4 | 3.7 | 11.0 | 89.2 | 83 | 56 | 52 | 16 | 37 | 109 | 0 | 8 | 3 | 0 | 0 | 4 | 0 | 4.27 |
| RP | Papelbon, J.Papelbon, Jonathan # >> | 27 | 2007 | R | 93 | 60 | 0 | 3 | 5 | 3.86 | .315 | 1.33 | 7.8 | 4.3 | 11.0 | 72.1 | 62 | 33 | 31 | 10 | 34 | 88 | 0 | 5 | 4 | 0 | 0 | 4 | 0 | 3.94 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 39 | 0 | 4 | 4 | 2.68 | .274 | 1.09 | 6.3 | 3.6 | 7.6 | 50.1 | 35 | 20 | 15 | 7 | 20 | 42 | 0 | 6 | 3 | 0 | 0 | 2 | 0 | 4.46 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 25 | 0 | 4 | 1 | 2.83 | .295 | 1.26 | 7.4 | 4.2 | 7.7 | 28.2 | 23 | 11 | 9 | 6 | 13 | 24 | 0 | 4 | 2 | 0 | 0 | 0 | 2 | 5.46 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 20 | 0 | 0 | 1 | 4.91 | .290 | 1.18 | 5.7 | 4.9 | 9.8 | 22.0 | 14 | 12 | 12 | 3 | 12 | 24 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.36 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 6 | 0 | 1 | 1 | 15.43 | .481 | 2.79 | 27.0 | 2.3 | 6.8 | 4.2 | 12 | 8 | 8 | 2 | 1 | 3 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 8.75 |