| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 27 | 27 | 18 | 6 | 2.56 | .229 | 0.88 | 5.9 | 2.0 | 7.9 | 214.2 | 141 | 66 | 61 | 20 | 48 | 189 | 9 | 0 | 0 | 3 | 23 | 2 | 5 | 3.15 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 26 | 26 | 14 | 7 | 4.38 | .323 | 1.39 | 7.8 | 4.7 | 4.5 | 193.0 | 168 | 97 | 94 | 18 | 101 | 96 | 3 | 0 | 0 | 0 | 16 | 7 | 2 | 4.90 |
| SP | Alexander, P.Alexander, Pete † # >> | 28 | 1915 | R | 88 | 26 | 26 | 11 | 6 | 3.69 | .268 | 1.09 | 7.6 | 2.2 | 5.3 | 204.2 | 173 | 85 | 84 | 23 | 50 | 119 | 8 | 0 | 0 | 1 | 15 | 2 | 3 | 4.06 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 26 | 26 | 13 | 10 | 4.48 | .321 | 1.39 | 9.2 | 3.3 | 7.8 | 189.0 | 194 | 95 | 94 | 23 | 69 | 163 | 2 | 0 | 0 | 0 | 12 | 5 | 3 | 4.03 |
| RP | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 84 | 53 | 0 | 5 | 2 | 2.59 | .251 | 1.01 | 7.2 | 2.0 | 7.2 | 41.2 | 33 | 12 | 12 | 4 | 9 | 33 | 0 | 7 | 3 | 0 | 0 | 0 | 0 | 3.32 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 79 | 29 | 0 | 3 | 0 | 3.28 | .295 | 1.22 | 7.9 | 3.4 | 7.9 | 24.2 | 21 | 9 | 9 | 3 | 9 | 21 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 4.13 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 24 | 0 | 1 | 2 | 4.26 | .329 | 1.42 | 8.5 | 4.3 | 5.7 | 19.0 | 18 | 9 | 9 | 4 | 9 | 12 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 6.05 |
| RP | Urbina, U.Urbina, Ugueth # >> | 24 | 1998 | R | 58 | 41 | 0 | 1 | 4 | 5.17 | .327 | 1.46 | 8.8 | 4.5 | 9.5 | 38.1 | 37 | 22 | 22 | 6 | 19 | 40 | 0 | 23 | 7 | 0 | 0 | 0 | 3 | 4.45 |
| CL | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 49 | 36 | 0 | 0 | 1 | 2.22 | .255 | 1.03 | 5.6 | 3.8 | 10.5 | 24.1 | 15 | 6 | 6 | 1 | 10 | 28 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.46 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 61 | 18 | 0 | 2 | 1 | 7.56 | .432 | 2.28 | 14.1 | 7.3 | 5.1 | 16.2 | 25 | 14 | 14 | 2 | 13 | 9 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 5.94 |