| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 28 | 28 | 11 | 8 | 3.47 | .276 | 1.13 | 7.9 | 2.3 | 9.4 | 187.0 | 165 | 76 | 72 | 21 | 47 | 196 | 1 | 0 | 0 | 0 | 20 | 2 | 0 | 3.15 |
| SP | Tiant, L.Tiant, Luis # >> | 28 | 1968 | R | 97 | 27 | 27 | 10 | 10 | 3.66 | .272 | 1.11 | 7.2 | 2.8 | 7.6 | 191.2 | 152 | 88 | 78 | 26 | 60 | 162 | 6 | 0 | 0 | 0 | 17 | 3 | 1 | 4.06 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 91 | 27 | 27 | 10 | 11 | 5.51 | .332 | 1.45 | 9.5 | 3.6 | 9.6 | 156.2 | 164 | 98 | 96 | 28 | 63 | 166 | 0 | 0 | 0 | 0 | 12 | 7 | 2 | 4.55 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 27 | 27 | 11 | 9 | 4.58 | .324 | 1.42 | 9.6 | 3.2 | 8.5 | 184.2 | 197 | 100 | 94 | 29 | 66 | 174 | 0 | 0 | 0 | 0 | 13 | 3 | 4 | 4.28 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 43 | 0 | 2 | 2 | 4.41 | .307 | 1.32 | 8.7 | 3.2 | 6.8 | 65.1 | 63 | 33 | 32 | 6 | 23 | 49 | 0 | 6 | 3 | 0 | 0 | 1 | 5 | 3.80 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 30 | 0 | 2 | 3 | 2.63 | .289 | 1.19 | 7.8 | 3.2 | 7.8 | 37.2 | 32 | 11 | 11 | 1 | 13 | 32 | 0 | 2 | 3 | 0 | 0 | 1 | 4 | 2.76 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 20 | 0 | 3 | 2 | 3.38 | .287 | 1.21 | 8.6 | 2.3 | 5.6 | 24.0 | 23 | 9 | 9 | 2 | 6 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.58 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 22 | 0 | 1 | 0 | 4.68 | .324 | 1.44 | 9.7 | 3.2 | 9.0 | 25.0 | 27 | 13 | 13 | 6 | 9 | 25 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 5.20 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 4 | 0 | 2 | 0 | 0.00 | .115 | 0.39 | 0.0 | 3.9 | 2.6 | 7.2 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.71 |