| SP | deGrom, J.deGrom, Jacob # >> | 33 | 2021 | R | 100 | 29 | 29 | 10 | 15 | 4.50 | .295 | 1.24 | 8.7 | 2.5 | 9.8 | 190.0 | 184 | 98 | 95 | 29 | 52 | 206 | 2 | 0 | 0 | 1 | 14 | 3 | 0 | 3.68 |
| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 28 | 28 | 7 | 15 | 4.71 | .313 | 1.33 | 9.3 | 2.7 | 8.0 | 198.2 | 205 | 114 | 104 | 26 | 59 | 175 | 4 | 0 | 0 | 0 | 14 | 7 | 7 | 3.94 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 27 | 27 | 10 | 11 | 3.76 | .297 | 1.24 | 7.3 | 3.8 | 7.9 | 179.2 | 146 | 78 | 75 | 23 | 76 | 158 | 1 | 0 | 0 | 0 | 17 | 6 | 5 | 4.28 |
| SP | Greinke, Z.Greinke, Zack # >> | 32 | 2015 | R | 94 | 27 | 27 | 10 | 12 | 3.86 | .285 | 1.16 | 7.9 | 2.6 | 5.3 | 200.1 | 175 | 88 | 86 | 28 | 57 | 118 | 6 | 0 | 0 | 1 | 17 | 7 | 2 | 4.60 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 70 | 0 | 3 | 3 | 3.01 | .296 | 1.24 | 8.5 | 2.7 | 10.1 | 92.2 | 87 | 31 | 31 | 9 | 28 | 103 | 0 | 11 | 5 | 0 | 0 | 2 | 0 | 3.01 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 66 | 0 | 7 | 6 | 4.22 | .305 | 1.28 | 7.9 | 3.6 | 8.9 | 79.0 | 69 | 37 | 37 | 10 | 32 | 78 | 0 | 10 | 3 | 0 | 0 | 3 | 0 | 4.00 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 46 | 0 | 2 | 4 | 3.98 | .306 | 1.33 | 7.1 | 4.8 | 8.2 | 43.0 | 34 | 20 | 19 | 5 | 23 | 39 | 0 | 6 | 1 | 0 | 0 | 0 | 3 | 4.30 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 3 | 0 | 0 | 0 | 0.00 | .353 | 1.64 | 12.0 | 6.0 | 6.0 | 3.2 | 4 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.67 |