| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 99 | 18 | 18 | 8 | 5 | 3.48 | .273 | 1.08 | 6.9 | 2.9 | 9.9 | 113.2 | 87 | 46 | 44 | 16 | 36 | 124 | 0 | 0 | 0 | 0 | 13 | 5 | 4 | 3.73 |
| SP | Bumgarner, M.Bumgarner, Madison >> | 26 | 2016 | L | 76 | 17 | 17 | 8 | 6 | 5.12 | .328 | 1.45 | 10.2 | 2.9 | 9.5 | 103.2 | 117 | 63 | 59 | 19 | 33 | 109 | 1 | 0 | 0 | 0 | 6 | 2 | 4 | 4.30 |
| SP | Shields, J.Shields, James >> | 30 | 2011 | R | 62 | 17 | 17 | 7 | 9 | 5.84 | .370 | 1.71 | 10.5 | 4.9 | 6.5 | 106.1 | 124 | 71 | 69 | 13 | 58 | 77 | 0 | 0 | 0 | 0 | 6 | 5 | 2 | 4.92 |
| SP | Porcello, R.Porcello, Rick >> | 27 | 2016 | R | 57 | 16 | 16 | 7 | 5 | 5.03 | .317 | 1.33 | 8.8 | 3.2 | 7.9 | 102.0 | 100 | 66 | 57 | 21 | 36 | 89 | 1 | 0 | 0 | 0 | 5 | 6 | 2 | 5.17 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 78 | 53 | 0 | 0 | 1 | 4.50 | .309 | 1.34 | 8.6 | 3.5 | 10.9 | 62.0 | 59 | 34 | 31 | 13 | 24 | 75 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 4.47 |
| SU | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 83 | 36 | 0 | 1 | 0 | 5.80 | .324 | 1.39 | 9.9 | 2.7 | 9.5 | 40.1 | 44 | 26 | 26 | 11 | 12 | 42 | 0 | 3 | 4 | 0 | 0 | 2 | 0 | 5.53 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 29 | 2017 | R | 100 | 40 | 0 | 3 | 4 | 3.92 | .312 | 1.31 | 6.9 | 4.8 | 11.5 | 39.0 | 30 | 18 | 17 | 3 | 21 | 50 | 0 | 18 | 1 | 0 | 0 | 2 | 0 | 3.21 |
| RP | McHugh, C.McHugh, Collin >> | 31 | 2018 | R | 60 | 40 | 0 | 4 | 1 | 4.56 | .311 | 1.31 | 8.4 | 3.4 | 9.0 | 47.1 | 44 | 24 | 24 | 6 | 18 | 47 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.94 |