| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 34 | 34 | 11 | 18 | 4.60 | .322 | 1.39 | 10.3 | 2.1 | 5.9 | 223.0 | 256 | 122 | 114 | 25 | 53 | 147 | 7 | 0 | 0 | 1 | 20 | 8 | 4 | 3.96 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 32 | 32 | 8 | 18 | 4.73 | .311 | 1.32 | 8.9 | 3.0 | 4.8 | 240.0 | 237 | 136 | 126 | 27 | 80 | 127 | 12 | 0 | 0 | 2 | 12 | 8 | 3 | 4.50 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 31 | 31 | 6 | 17 | 5.49 | .332 | 1.49 | 9.9 | 3.5 | 8.5 | 218.0 | 239 | 142 | 133 | 26 | 85 | 207 | 5 | 0 | 0 | 1 | 10 | 1 | 10 | 3.83 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 53 | 0 | 7 | 3 | 4.74 | .324 | 1.42 | 8.3 | 4.6 | 7.3 | 62.2 | 57 | 37 | 33 | 7 | 32 | 50 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.45 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 39 | 0 | 4 | 2 | 2.76 | .276 | 1.14 | 6.8 | 3.5 | 6.6 | 49.0 | 37 | 18 | 15 | 4 | 19 | 36 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.76 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 30 | 0 | 0 | 2 | 4.50 | .349 | 1.57 | 8.4 | 5.8 | 7.4 | 28.0 | 26 | 18 | 14 | 4 | 18 | 23 | 0 | 2 | 1 | 0 | 0 | 1 | 3 | 5.25 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 30 | 0 | 2 | 0 | 2.25 | .299 | 1.28 | 7.0 | 4.5 | 7.0 | 36.0 | 28 | 12 | 9 | 5 | 18 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.75 |