| SP | Martinez, P.Martinez, Pedro $$ >> | 29 | 2000 | R | 100 | 39 | 39 | 13 | 14 | 4.51 | .307 | 1.30 | 9.1 | 2.7 | 8.6 | 245.2 | 247 | 130 | 123 | 40 | 73 | 233 | 3 | 0 | 0 | 0 | 20 | 7 | 6 | 4.20 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 37 | 36 | 15 | 7 | 4.22 | .311 | 1.33 | 9.0 | 3.0 | 8.4 | 226.1 | 226 | 112 | 106 | 22 | 76 | 211 | 2 | 0 | 0 | 0 | 19 | 5 | 3 | 3.47 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 78 | 35 | 35 | 14 | 11 | 4.73 | .294 | 1.23 | 8.7 | 2.3 | 5.4 | 217.0 | 210 | 124 | 114 | 35 | 56 | 129 | 6 | 0 | 0 | 0 | 13 | 5 | 3 | 4.75 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 68 | 32 | 31 | 12 | 8 | 5.93 | .350 | 1.59 | 11.0 | 3.3 | 8.7 | 168.1 | 206 | 114 | 111 | 27 | 62 | 162 | 0 | 1 | 0 | 0 | 12 | 4 | 2 | 4.34 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 94 | 0 | 5 | 11 | 3.24 | .283 | 1.15 | 7.1 | 3.3 | 9.6 | 97.1 | 76 | 37 | 35 | 13 | 36 | 103 | 0 | 40 | 7 | 0 | 0 | 3 | 7 | 3.82 |
| SU | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 94 | 98 | 0 | 6 | 2 | 2.98 | .282 | 1.15 | 6.1 | 4.2 | 9.7 | 142.0 | 96 | 56 | 47 | 7 | 67 | 153 | 0 | 7 | 4 | 0 | 0 | 4 | 0 | 2.99 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 104 | 0 | 10 | 5 | 4.11 | .298 | 1.25 | 8.4 | 2.9 | 8.6 | 127.0 | 118 | 64 | 58 | 19 | 41 | 122 | 0 | 0 | 3 | 0 | 0 | 3 | 0 | 4.06 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 83 | 0 | 6 | 5 | 4.19 | .355 | 1.64 | 10.0 | 4.9 | 9.4 | 81.2 | 90 | 42 | 38 | 7 | 44 | 85 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.69 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 72 | 0 | 6 | 4 | 3.83 | .306 | 1.29 | 7.9 | 3.8 | 8.5 | 91.2 | 80 | 41 | 39 | 10 | 38 | 86 | 0 | 3 | 0 | 0 | 0 | 3 | 1 | 3.89 |