| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 16 | 16 | 4 | 8 | 4.39 | .317 | 1.34 | 9.8 | 2.3 | 8.8 | 110.2 | 120 | 57 | 54 | 16 | 28 | 107 | 2 | 0 | 0 | 0 | 11 | 6 | 1 | 3.87 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 15 | 15 | 5 | 6 | 3.92 | .307 | 1.28 | 8.3 | 3.3 | 4.0 | 82.2 | 76 | 37 | 36 | 9 | 30 | 36 | 0 | 0 | 0 | 0 | 6 | 4 | 3 | 4.79 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 15 | 15 | 5 | 4 | 4.41 | .315 | 1.37 | 9.6 | 2.8 | 4.7 | 114.1 | 122 | 58 | 56 | 10 | 35 | 59 | 0 | 0 | 0 | 0 | 7 | 1 | 0 | 4.05 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 15 | 15 | 5 | 9 | 7.22 | .359 | 1.68 | 11.2 | 3.9 | 4.4 | 96.0 | 119 | 77 | 77 | 21 | 42 | 47 | 1 | 0 | 0 | 0 | 1 | 0 | 5 | 6.18 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 15 | 15 | 7 | 6 | 5.05 | .345 | 1.56 | 10.8 | 3.3 | 4.3 | 108.2 | 130 | 75 | 61 | 16 | 40 | 52 | 5 | 0 | 0 | 1 | 6 | 2 | 2 | 5.13 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 40 | 0 | 4 | 2 | 3.04 | .278 | 1.15 | 7.9 | 2.5 | 9.7 | 50.1 | 44 | 18 | 17 | 4 | 14 | 54 | 0 | 6 | 2 | 0 | 0 | 0 | 1 | 2.72 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 35 | 0 | 2 | 0 | 6.20 | .366 | 1.67 | 9.8 | 5.2 | 8.2 | 45.0 | 49 | 31 | 31 | 3 | 26 | 41 | 0 | 7 | 6 | 0 | 0 | 3 | 1 | 3.98 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 25 | 0 | 2 | 2 | 6.31 | .353 | 1.60 | 11.5 | 3.2 | 8.3 | 25.2 | 32 | 18 | 18 | 3 | 9 | 23 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 3.92 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 17 | 0 | 2 | 0 | 3.66 | .314 | 1.37 | 9.5 | 3.3 | 10.9 | 19.2 | 20 | 8 | 8 | 1 | 7 | 23 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2.37 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 54 | 19 | 0 | 0 | 1 | 4.13 | .241 | 0.95 | 8.4 | 0.3 | 6.8 | 28.1 | 26 | 13 | 13 | 5 | 1 | 21 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 3.93 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 1 | 1 | 1 | 0 | 1.35 | .310 | 1.35 | 10.5 | 3.0 | 7.5 | 6.2 | 7 | 1 | 1 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2.33 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 6 | 0 | 1 | 1 | 9.00 | .357 | 1.67 | 10.5 | 4.5 | 7.5 | 6.0 | 7 | 6 | 6 | 1 | 3 | 5 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.00 |