| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 98 | 13 | 13 | 6 | 3 | 3.61 | .266 | 1.06 | 7.4 | 2.2 | 10.1 | 94.2 | 77 | 40 | 38 | 15 | 23 | 105 | 2 | 0 | 0 | 0 | 8 | 3 | 3 | 3.67 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 13 | 13 | 2 | 2 | 6.16 | .348 | 1.57 | 11.4 | 2.9 | 8.6 | 68.2 | 86 | 52 | 47 | 20 | 22 | 65 | 0 | 0 | 0 | 0 | 5 | 2 | 2 | 5.97 |
| SP | Smoltz, J.Smoltz, John >> | 29 | 1996 | R | 62 | 13 | 12 | 3 | 8 | 5.24 | .339 | 1.51 | 9.7 | 4.0 | 7.6 | 77.1 | 83 | 51 | 45 | 16 | 34 | 65 | 1 | 0 | 0 | 0 | 7 | 2 | 3 | 5.42 |
| SP | DeLeon, J.DeLeon, Jose # >> | 29 | 1989 | R | 60 | 14 | 12 | 2 | 6 | 4.42 | .328 | 1.44 | 8.5 | 4.4 | 6.1 | 77.1 | 73 | 46 | 38 | 16 | 38 | 52 | 0 | 0 | 0 | 0 | 6 | 2 | 5 | 5.91 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 35 | 0 | 1 | 5 | 4.78 | .310 | 1.35 | 9.4 | 2.8 | 8.8 | 49.0 | 51 | 27 | 26 | 8 | 15 | 48 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 4.08 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 80 | 29 | 0 | 2 | 5 | 4.17 | .349 | 1.55 | 11.0 | 3.3 | 9.5 | 36.2 | 44 | 18 | 17 | 8 | 13 | 38 | 0 | 3 | 3 | 0 | 0 | 2 | 1 | 5.03 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 79 | 20 | 0 | 1 | 2 | 5.82 | .309 | 1.34 | 9.9 | 2.6 | 9.9 | 21.2 | 23 | 14 | 14 | 2 | 6 | 23 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.90 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 74 | 14 | 0 | 0 | 2 | 7.79 | .350 | 1.62 | 12.2 | 2.6 | 7.9 | 17.1 | 23 | 17 | 15 | 5 | 5 | 15 | 0 | 0 | 3 | 0 | 0 | 0 | 1 | 5.94 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 11 | 0 | 0 | 0 | 4.80 | .357 | 1.60 | 10.2 | 4.2 | 9.0 | 15.0 | 17 | 8 | 8 | 5 | 7 | 15 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 6.93 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 60 | 18 | 0 | 1 | 0 | 1.89 | .260 | 1.05 | 4.3 | 5.2 | 9.5 | 19.0 | 9 | 4 | 4 | 2 | 11 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 58 | 3 | 0 | 1 | 0 | 3.86 | .300 | 1.29 | 6.8 | 6.8 | 2.3 | 4.2 | 3 | 2 | 2 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.75 |