| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 13 | 13 | 4 | 6 | 4.15 | .303 | 1.30 | 8.3 | 3.6 | 8.5 | 86.2 | 79 | 42 | 40 | 10 | 34 | 81 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | 3.81 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 13 | 13 | 3 | 4 | 3.48 | .336 | 1.51 | 7.4 | 6.3 | 10.2 | 67.1 | 55 | 27 | 26 | 5 | 47 | 76 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 3.81 |
| SP | Higuera, T.Higuera, Teddy # >> | 30 | 1988 | L | 65 | 13 | 13 | 3 | 6 | 4.88 | .332 | 1.46 | 10.0 | 3.1 | 7.9 | 83.0 | 92 | 45 | 45 | 14 | 29 | 73 | 1 | 0 | 0 | 0 | 5 | 3 | 0 | 4.59 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 33 | 0 | 4 | 2 | 3.04 | .317 | 1.37 | 7.7 | 4.8 | 11.5 | 47.1 | 40 | 16 | 16 | 2 | 25 | 60 | 0 | 1 | 3 | 0 | 0 | 1 | 2 | 2.66 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 94 | 37 | 0 | 3 | 2 | 3.19 | .291 | 1.23 | 7.7 | 3.4 | 7.7 | 48.0 | 41 | 19 | 17 | 8 | 18 | 41 | 0 | 4 | 6 | 0 | 0 | 0 | 2 | 4.58 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 90 | 27 | 0 | 3 | 5 | 4.15 | .283 | 1.15 | 8.1 | 2.4 | 9.9 | 30.1 | 27 | 14 | 14 | 6 | 8 | 33 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 4.30 |
| RP | Chapman, A.Chapman, Aroldis >> | 24 | 2012 | L | 88 | 18 | 0 | 2 | 0 | 1.99 | .253 | 1.01 | 2.9 | 6.5 | 13.5 | 22.2 | 7 | 5 | 5 | 1 | 16 | 33 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.77 |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 54 | 4 | 0 | 0 | 0 | 5.40 | .324 | 1.44 | 9.0 | 4.5 | 9.0 | 8.1 | 8 | 5 | 5 | 2 | 4 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.75 |