| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 94 | 37 | 37 | 18 | 8 | 2.71 | .258 | 1.02 | 6.7 | 2.6 | 6.8 | 268.2 | 199 | 85 | 81 | 29 | 76 | 201 | 6 | 0 | 0 | 2 | 25 | 5 | 7 | 3.81 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 90 | 35 | 35 | 14 | 12 | 3.74 | .272 | 1.11 | 8.1 | 1.9 | 5.7 | 245.2 | 220 | 105 | 102 | 31 | 52 | 155 | 9 | 0 | 0 | 2 | 23 | 3 | 5 | 4.05 |
| SP | Sutton, D.Sutton, Don † >> | 27 | 1972 | R | 86 | 34 | 34 | 19 | 13 | 4.20 | .312 | 1.34 | 8.6 | 3.5 | 5.8 | 233.1 | 223 | 114 | 109 | 28 | 90 | 149 | 8 | 0 | 0 | 2 | 18 | 4 | 10 | 4.49 |
| SP | Nola, A.Nola, Aaron † # >> | 25 | 2018 | R | 79 | 33 | 33 | 20 | 10 | 3.00 | .265 | 1.07 | 6.9 | 2.7 | 8.5 | 216.0 | 166 | 73 | 72 | 24 | 65 | 203 | 0 | 0 | 0 | 0 | 24 | 3 | 3 | 3.51 |
| SP | Gooden, D.Gooden, Dwight † >> | 21 | 1985 | R | 75 | 31 | 31 | 11 | 8 | 4.14 | .318 | 1.36 | 8.7 | 3.5 | 7.3 | 222.0 | 214 | 108 | 102 | 31 | 87 | 179 | 6 | 0 | 0 | 1 | 18 | 9 | 3 | 4.50 |
| CL | Eckersley, D.Eckersley, Dennis † >> | 36 | 1990 | R | 85 | 76 | 0 | 7 | 10 | 3.80 | .280 | 1.15 | 8.7 | 1.7 | 10.1 | 68.2 | 66 | 29 | 29 | 11 | 13 | 76 | 0 | 42 | 6 | 0 | 0 | 1 | 0 | 3.49 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 80 | 61 | 0 | 3 | 1 | 3.44 | .258 | 1.03 | 5.7 | 3.6 | 8.5 | 68.0 | 43 | 28 | 26 | 9 | 27 | 64 | 0 | 5 | 0 | 0 | 0 | 1 | 2 | 4.07 |
| RP | Hoffman, T.Hoffman, Trevor # >> | 31 | 1998 | R | 72 | 37 | 0 | 7 | 1 | 5.67 | .310 | 1.32 | 9.0 | 3.0 | 9.5 | 33.1 | 33 | 21 | 21 | 8 | 11 | 35 | 0 | 3 | 0 | 0 | 0 | 1 | 4 | 5.12 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 66 | 18 | 0 | 1 | 2 | 4.08 | .361 | 1.70 | 11.1 | 4.8 | 5.8 | 17.2 | 21 | 10 | 8 | 3 | 9 | 11 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 5.59 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 64 | 24 | 0 | 1 | 1 | 5.33 | .333 | 1.50 | 9.4 | 4.3 | 7.2 | 25.1 | 26 | 15 | 15 | 6 | 12 | 20 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.96 |