| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 74 | 25 | 25 | 13 | 10 | 4.24 | .302 | 1.28 | 8.1 | 3.5 | 4.8 | 193.0 | 174 | 98 | 91 | 21 | 74 | 102 | 11 | 0 | 0 | 1 | 10 | 3 | 3 | 4.55 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 25 | 25 | 8 | 8 | 4.94 | .335 | 1.51 | 10.0 | 3.6 | 5.2 | 144.0 | 160 | 89 | 79 | 18 | 58 | 83 | 0 | 0 | 0 | 0 | 10 | 0 | 2 | 4.68 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 24 | 23 | 8 | 10 | 7.03 | .363 | 1.68 | 10.9 | 4.3 | 5.5 | 138.1 | 167 | 109 | 108 | 19 | 66 | 84 | 2 | 0 | 0 | 0 | 4 | 4 | 5 | 5.09 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 64 | 0 | 4 | 1 | 3.31 | .281 | 1.12 | 6.7 | 3.4 | 10.4 | 92.1 | 68 | 34 | 34 | 9 | 35 | 106 | 0 | 15 | 2 | 0 | 0 | 5 | 7 | 3.27 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 51 | 0 | 3 | 4 | 4.48 | .294 | 1.24 | 7.4 | 3.8 | 10.3 | 62.1 | 51 | 31 | 31 | 13 | 26 | 71 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 4.74 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 42 | 0 | 3 | 2 | 2.52 | .233 | 0.91 | 7.1 | 1.2 | 7.3 | 53.2 | 42 | 18 | 15 | 8 | 7 | 43 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 3.74 |
| RP | Treinen, B.Treinen, Blake # >> | 30 | 2018 | R | 80 | 26 | 0 | 3 | 0 | 5.52 | .367 | 1.74 | 9.3 | 6.5 | 7.8 | 29.1 | 30 | 20 | 18 | 4 | 21 | 25 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 5.24 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 27 | 0 | 3 | 3 | 2.53 | .232 | 0.91 | 5.3 | 2.8 | 10.1 | 32.0 | 19 | 11 | 9 | 6 | 10 | 36 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 4.13 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 62 | 18 | 0 | 0 | 0 | 3.50 | .280 | 1.11 | 7.0 | 3.0 | 5.0 | 18.0 | 14 | 7 | 7 | 0 | 6 | 10 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.06 |