| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 97 | 25 | 25 | 15 | 5 | 3.05 | .300 | 1.24 | 7.6 | 3.5 | 7.5 | 186.0 | 157 | 67 | 63 | 15 | 73 | 155 | 6 | 0 | 0 | 0 | 18 | 9 | 3 | 3.70 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 25 | 25 | 11 | 6 | 4.41 | .285 | 1.19 | 8.7 | 2.1 | 4.5 | 149.0 | 144 | 75 | 73 | 15 | 34 | 75 | 3 | 0 | 0 | 0 | 13 | 0 | 1 | 3.99 |
| SP | Brown, M.Brown, Mordecai # >> | 32 | 1908 | R | 85 | 24 | 24 | 9 | 7 | 4.29 | .290 | 1.21 | 8.5 | 2.3 | 3.3 | 151.0 | 143 | 75 | 72 | 9 | 39 | 56 | 3 | 0 | 0 | 2 | 11 | 3 | 7 | 3.87 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 26 | 24 | 9 | 5 | 4.12 | .309 | 1.32 | 9.0 | 2.9 | 5.9 | 153.0 | 153 | 72 | 70 | 19 | 49 | 101 | 4 | 0 | 0 | 1 | 12 | 3 | 5 | 4.31 |
| CL | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 56 | 0 | 5 | 12 | 3.86 | .284 | 1.16 | 7.0 | 3.4 | 8.0 | 63.0 | 49 | 28 | 27 | 7 | 24 | 56 | 0 | 26 | 2 | 0 | 0 | 2 | 1 | 3.90 |
| SU | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 59 | 0 | 3 | 4 | 4.04 | .320 | 1.41 | 7.1 | 5.7 | 10.0 | 62.1 | 49 | 32 | 28 | 8 | 39 | 69 | 0 | 5 | 8 | 0 | 0 | 0 | 1 | 4.34 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 59 | 0 | 3 | 2 | 2.59 | .308 | 1.33 | 7.0 | 5.0 | 11.0 | 66.0 | 51 | 20 | 19 | 3 | 37 | 81 | 0 | 1 | 2 | 0 | 0 | 0 | 10 | 2.82 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 51 | 0 | 6 | 2 | 2.59 | .247 | 0.97 | 6.3 | 2.4 | 10.2 | 59.0 | 41 | 19 | 17 | 6 | 16 | 67 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 2.92 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 36 | 0 | 1 | 0 | 3.32 | .303 | 1.25 | 7.0 | 4.5 | 9.9 | 40.2 | 31 | 15 | 15 | 4 | 20 | 44 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 3.75 |