| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 26 | 26 | 4 | 10 | 4.60 | .298 | 1.26 | 8.5 | 2.9 | 9.9 | 158.1 | 149 | 85 | 81 | 18 | 51 | 174 | 0 | 0 | 0 | 0 | 13 | 2 | 0 | 3.28 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 25 | 25 | 5 | 17 | 6.57 | .326 | 1.43 | 10.2 | 2.6 | 8.1 | 137.0 | 156 | 112 | 100 | 30 | 40 | 123 | 3 | 0 | 0 | 0 | 8 | 3 | 3 | 4.99 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 24 | 24 | 11 | 8 | 4.56 | .303 | 1.26 | 9.5 | 1.9 | 4.6 | 169.2 | 179 | 93 | 86 | 23 | 35 | 87 | 5 | 0 | 0 | 0 | 11 | 7 | 4 | 4.49 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 68 | 0 | 4 | 7 | 5.56 | .350 | 1.61 | 9.5 | 5.0 | 6.3 | 89.0 | 94 | 60 | 55 | 12 | 49 | 62 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 5.04 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 60 | 0 | 7 | 5 | 5.40 | .344 | 1.57 | 9.9 | 4.2 | 9.1 | 70.0 | 77 | 42 | 42 | 17 | 33 | 71 | 0 | 5 | 4 | 0 | 0 | 0 | 0 | 5.54 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 31 | 0 | 2 | 2 | 1.39 | .265 | 1.06 | 5.8 | 3.8 | 5.2 | 45.1 | 29 | 9 | 7 | 4 | 19 | 26 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 4.33 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 69 | 37 | 0 | 1 | 0 | 4.15 | .301 | 1.27 | 7.1 | 4.4 | 6.1 | 43.1 | 34 | 21 | 20 | 3 | 21 | 29 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.09 |