| SP | Maddux, G.Maddux, Greg † >> | 26 | 1992 | R | 97 | 20 | 20 | 11 | 9 | 3.05 | .295 | 1.25 | 8.3 | 2.9 | 5.1 | 165.1 | 152 | 65 | 56 | 4 | 54 | 94 | 10 | 0 | 0 | 2 | 12 | 2 | 2 | 3.19 |
| SP | Hammel, J.Hammel, Jason # >> | 34 | 2016 | R | 78 | 19 | 19 | 12 | 3 | 4.09 | .294 | 1.24 | 8.7 | 2.5 | 6.4 | 105.2 | 102 | 53 | 48 | 12 | 29 | 75 | 0 | 0 | 0 | 0 | 10 | 1 | 4 | 3.91 |
| SP | Wiltse, H.Wiltse, Hooks >> | 32 | 1911 | L | 72 | 18 | 18 | 5 | 8 | 5.64 | .359 | 1.66 | 11.8 | 3.2 | 4.5 | 107.0 | 140 | 70 | 67 | 12 | 38 | 54 | 0 | 0 | 0 | 0 | 6 | 2 | 4 | 4.57 |
| SP | Sutcliffe, R.Sutcliffe, Rick >> | 29 | 1985 | R | 65 | 18 | 18 | 5 | 5 | 4.86 | .350 | 1.59 | 10.3 | 4.0 | 5.6 | 111.0 | 127 | 64 | 60 | 7 | 49 | 69 | 1 | 0 | 0 | 0 | 8 | 3 | 10 | 3.98 |
| RP | Iglesias, R.Iglesias, Raisel >> | 32 | 2022 | R | 98 | 58 | 0 | 4 | 2 | 4.89 | .310 | 1.31 | 8.0 | 3.9 | 9.2 | 53.1 | 47 | 32 | 29 | 4 | 23 | 54 | 0 | 3 | 0 | 0 | 0 | 2 | 3 | 3.36 |
| RP | Harris, W.Harris, Will >> | 28 | 2013 | R | 60 | 49 | 0 | 1 | 1 | 2.09 | .326 | 1.45 | 10.2 | 3.1 | 8.5 | 38.2 | 43 | 11 | 9 | 2 | 13 | 36 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.82 |
| RP | Diekman, J.Diekman, Jake >> | 32 | 2019 | L | 52 | 43 | 0 | 1 | 1 | 6.16 | .313 | 1.37 | 8.4 | 4.2 | 9.0 | 30.2 | 28 | 21 | 21 | 0 | 14 | 30 | 0 | 6 | 1 | 0 | 0 | 0 | 2 | 2.40 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 35 | 2013 | L | 16 | 26 | 0 | 2 | 0 | 1.82 | .253 | 0.97 | 7.5 | 1.5 | 7.9 | 24.2 | 20 | 5 | 5 | 2 | 4 | 21 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 2.96 |
| RP | Quisenberry, D.Quisenberry, Dan † >> | 29 | 1982 | R | 74 | 35 | 0 | 5 | 2 | 2.28 | .274 | 1.09 | 8.1 | 1.8 | 4.2 | 51.1 | 46 | 15 | 13 | 1 | 10 | 24 | 0 | 11 | 1 | 0 | 0 | 2 | 0 | 3.02 |