| SP | Santana, J.Santana, Johan † >> | 25 | 2004 | L | 91 | 20 | 20 | 8 | 6 | 2.78 | .263 | 1.06 | 7.1 | 2.5 | 10.2 | 139.0 | 109 | 44 | 43 | 14 | 39 | 157 | 1 | 0 | 0 | 1 | 15 | 1 | 4 | 2.91 |
| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 19 | 19 | 11 | 6 | 2.37 | .234 | 0.91 | 6.0 | 2.2 | 9.1 | 148.0 | 99 | 42 | 39 | 19 | 36 | 150 | 8 | 0 | 0 | 0 | 16 | 1 | 3 | 3.39 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 93 | 19 | 19 | 10 | 5 | 4.22 | .301 | 1.25 | 8.0 | 3.3 | 7.0 | 132.1 | 118 | 64 | 62 | 10 | 48 | 102 | 1 | 0 | 0 | 0 | 12 | 5 | 7 | 3.64 |
| SP | Carlton, S.Carlton, Steve # >> | 28 | 1972 | L | 68 | 18 | 18 | 7 | 6 | 4.56 | .297 | 1.24 | 8.4 | 2.8 | 6.6 | 118.1 | 110 | 60 | 60 | 17 | 37 | 86 | 3 | 0 | 0 | 0 | 10 | 3 | 0 | 4.43 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 39 | 0 | 3 | 4 | 3.41 | .288 | 1.16 | 6.8 | 3.6 | 10.2 | 37.0 | 28 | 14 | 14 | 2 | 15 | 42 | 0 | 27 | 1 | 0 | 0 | 2 | 4 | 2.81 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 34 | 0 | 0 | 4 | 3.86 | .263 | 0.99 | 6.8 | 2.2 | 8.5 | 37.1 | 28 | 17 | 16 | 6 | 9 | 35 | 0 | 5 | 5 | 0 | 0 | 3 | 0 | 4.19 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 86 | 35 | 0 | 5 | 1 | 5.19 | .346 | 1.56 | 11.4 | 2.9 | 8.7 | 34.2 | 43 | 21 | 20 | 3 | 11 | 33 | 0 | 3 | 3 | 0 | 0 | 1 | 0 | 3.26 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 79 | 24 | 0 | 2 | 1 | 2.49 | .253 | 0.97 | 6.0 | 3.0 | 8.1 | 21.2 | 14 | 6 | 6 | 1 | 7 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.95 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 13 | 0 | 0 | 0 | 3.86 | .349 | 1.50 | 7.0 | 7.0 | 9.0 | 9.1 | 7 | 4 | 4 | 2 | 7 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.56 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 66 | 10 | 0 | 1 | 0 | 0.79 | .292 | 1.24 | 4.1 | 7.4 | 4.9 | 11.1 | 5 | 1 | 1 | 0 | 9 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.36 |