| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 18 | 18 | 6 | 10 | 3.95 | .296 | 1.26 | 8.3 | 3.1 | 8.9 | 123.0 | 113 | 56 | 54 | 13 | 42 | 122 | 3 | 0 | 0 | 2 | 11 | 0 | 5 | 3.41 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 72 | 18 | 18 | 5 | 10 | 6.87 | .358 | 1.63 | 10.8 | 3.9 | 5.9 | 94.1 | 113 | 75 | 72 | 30 | 41 | 62 | 0 | 0 | 0 | 0 | 7 | 4 | 2 | 7.27 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 17 | 17 | 5 | 9 | 4.30 | .302 | 1.26 | 8.1 | 3.2 | 6.1 | 113.0 | 102 | 58 | 54 | 13 | 40 | 77 | 0 | 0 | 0 | 0 | 7 | 5 | 2 | 4.33 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 21 | 1981 | L | 61 | 17 | 17 | 5 | 10 | 5.40 | .353 | 1.61 | 9.6 | 4.9 | 6.3 | 108.1 | 115 | 67 | 65 | 17 | 59 | 75 | 1 | 0 | 0 | 0 | 6 | 3 | 2 | 5.38 |
| SP | Wilson, D.Wilson, Don # >> | 26 | 1971 | R | 59 | 16 | 16 | 6 | 8 | 4.31 | .306 | 1.28 | 8.8 | 2.8 | 6.1 | 112.2 | 109 | 60 | 54 | 21 | 35 | 76 | 6 | 0 | 0 | 1 | 9 | 5 | 2 | 5.15 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 47 | 0 | 0 | 2 | 3.55 | .306 | 1.29 | 9.0 | 2.6 | 10.4 | 58.1 | 58 | 24 | 23 | 3 | 17 | 67 | 0 | 5 | 2 | 0 | 0 | 2 | 0 | 2.34 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 39 | 0 | 1 | 2 | 3.11 | .298 | 1.23 | 8.4 | 2.7 | 8.8 | 46.1 | 43 | 18 | 16 | 6 | 14 | 45 | 0 | 3 | 1 | 0 | 0 | 2 | 2 | 3.78 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 62 | 33 | 0 | 2 | 0 | 4.54 | .311 | 1.35 | 9.2 | 3.2 | 10.9 | 37.2 | 38 | 19 | 19 | 4 | 13 | 45 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 3.03 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 46 | 20 | 0 | 1 | 1 | 1.33 | .190 | 0.70 | 5.7 | 0.7 | 9.0 | 27.0 | 17 | 4 | 4 | 1 | 2 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.70 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 49 | 7 | 0 | 1 | 1 | 4.96 | .300 | 1.29 | 9.6 | 2.3 | 9.0 | 16.1 | 17 | 9 | 9 | 3 | 4 | 16 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.19 |