| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 19 | 19 | 7 | 4 | 2.05 | .232 | 0.88 | 6.1 | 1.9 | 9.1 | 136.0 | 92 | 34 | 31 | 13 | 28 | 137 | 0 | 0 | 0 | 0 | 17 | 3 | 0 | 2.91 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 18 | 18 | 10 | 4 | 2.52 | .272 | 1.11 | 5.8 | 4.3 | 8.7 | 114.1 | 73 | 35 | 32 | 8 | 54 | 110 | 0 | 0 | 0 | 0 | 14 | 1 | 0 | 3.43 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 76 | 17 | 17 | 7 | 5 | 3.21 | .268 | 1.08 | 8.1 | 1.6 | 5.1 | 126.1 | 114 | 49 | 45 | 18 | 23 | 71 | 6 | 0 | 0 | 2 | 11 | 2 | 4 | 4.33 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 87 | 47 | 0 | 4 | 4 | 4.81 | .298 | 1.24 | 7.4 | 3.7 | 9.5 | 58.0 | 48 | 31 | 31 | 6 | 24 | 61 | 0 | 0 | 3 | 0 | 0 | 2 | 4 | 3.59 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 38 | 0 | 2 | 2 | 3.69 | .287 | 1.21 | 8.4 | 2.5 | 7.0 | 46.1 | 43 | 22 | 19 | 6 | 13 | 36 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.98 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 31 | 0 | 0 | 2 | 3.20 | .269 | 1.11 | 6.5 | 3.6 | 11.5 | 25.1 | 18 | 10 | 9 | 6 | 10 | 32 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.76 |
| RP | Williamson, S.Williamson, Scott >> | 23 | 1999 | R | 43 | 21 | 0 | 2 | 1 | 5.09 | .369 | 1.75 | 9.0 | 7.4 | 11.1 | 17.2 | 17 | 10 | 10 | 3 | 14 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 5.29 |
| CL | Edwards, C.Edwards, Carl † >> | 24 | 2016 | R | 93 | 39 | 0 | 0 | 6 | 2.63 | .259 | 1.02 | 5.0 | 4.2 | 9.4 | 41.0 | 23 | 12 | 12 | 3 | 19 | 43 | 0 | 23 | 1 | 0 | 0 | 1 | 3 | 3.32 |