| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 92 | 19 | 19 | 7 | 7 | 3.92 | .281 | 1.17 | 8.1 | 2.5 | 8.5 | 133.0 | 119 | 58 | 58 | 20 | 37 | 125 | 3 | 0 | 0 | 1 | 13 | 0 | 2 | 3.91 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 89 | 18 | 18 | 11 | 6 | 3.74 | .270 | 1.10 | 7.5 | 2.5 | 8.1 | 122.2 | 101 | 52 | 51 | 19 | 34 | 110 | 3 | 0 | 0 | 0 | 11 | 1 | 2 | 4.08 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 70 | 18 | 18 | 5 | 7 | 4.89 | .329 | 1.47 | 9.5 | 3.8 | 6.8 | 108.2 | 114 | 64 | 59 | 17 | 46 | 82 | 0 | 0 | 0 | 0 | 7 | 0 | 5 | 4.81 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 67 | 17 | 17 | 7 | 8 | 4.50 | .324 | 1.41 | 9.2 | 3.5 | 6.2 | 112.0 | 115 | 56 | 56 | 11 | 43 | 77 | 4 | 0 | 0 | 0 | 8 | 3 | 5 | 4.13 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 81 | 44 | 0 | 2 | 1 | 1.87 | .228 | 0.83 | 4.3 | 3.3 | 11.1 | 57.2 | 27 | 12 | 12 | 8 | 21 | 70 | 0 | 5 | 1 | 0 | 0 | 3 | 3 | 3.63 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 77 | 18 | 0 | 1 | 0 | 3.28 | .245 | 0.97 | 6.8 | 2.3 | 9.0 | 24.2 | 18 | 10 | 9 | 1 | 6 | 24 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 2.29 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 12 | 0 | 2 | 1 | 3.12 | .288 | 1.21 | 8.5 | 2.6 | 7.9 | 17.1 | 16 | 6 | 6 | 3 | 5 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.41 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 62 | 7 | 0 | 0 | 0 | 12.27 | .450 | 2.45 | 24.0 | 3.0 | 12.0 | 3.2 | 8 | 5 | 5 | 2 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.00 |
| CL | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 96 | 33 | 0 | 2 | 0 | 1.31 | .248 | 0.93 | 6.6 | 1.9 | 10.3 | 34.1 | 25 | 5 | 5 | 1 | 7 | 39 | 0 | 25 | 3 | 0 | 0 | 2 | 0 | 1.88 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 16 | 0 | 1 | 1 | 4.76 | .320 | 1.41 | 6.4 | 6.4 | 5.8 | 17.0 | 12 | 9 | 9 | 2 | 12 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.35 |